Level C· Early Human Research
Potential drawbacks in cell-assisted lipotransfer: A systematic review of existing reports
Huang S., Zhao W., Wang Z., Chang P.
Reviewed 57 CAL studies focusing on drawbacks and risks such as graft liquefaction/resorption and the absence of standardised guidelines.
- Study type
- Systematic Review
- Journal
- Molecular Medicine Reports (2016)
- Country
- China
- Sample size
- —
- Follow-up
- Not applicable (literature review)
- PMID
- 26677061
- DOI
- 10.3892/mmr.2015.4682
What was studied
Drawbacks, risks and regulatory gaps in the clinical use of CAL.
Methods
- • Reviewed 57 publications, of which seven described actual clinical application.
Key findings
- • Clinical use was concentrated in breast augmentation and soft-tissue augmentation.
- • The authors called for clear criteria and guidelines before widespread use.
Limitations
- • Narrative-style review without quantitative analysis.
- • 2016 data may be partly outdated.
What this study does not prove
- • This study does not prove SVF is an approved treatment or a replacement for standard care.
- • Limited follow-up cannot indicate long-term outcomes.
Clinical interpretation
A risk-focused counterweight to studies that report only positive outcomes.
Evidence level: Early Human Research