Level D· Scientific groundwork from lab and animal studiesLaboratory StudyPubMed

ILC2s chew the fat.

Ricardo-Gonzalez RR., Locksley RM.

Laboratory Study on Face & Skin, Systemic / IV, published in J Exp Med (2019) — summary generated from the PubMed abstract.

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Level D· Scientific groundwork from lab and animal studiesEvidence level of this study

Evidence from laboratory and animal studies provides groundwork for understanding mechanisms and potential before human studies continue.

  • Level A · Stronger Clinical Evidence
  • Level B · Emerging clinical evidence with positive signals
  • Level C · Early human research exploring benefits
  • Level D · Scientific groundwork from lab and animal studies
  • Emerging · Emerging topic under active research
Read the A–D evidence level guide

This page is generated from the PubMed record. The Thai description is an automated summary of bibliographic fields and the abstract, not a full translation, and is not medical advice.

Study type
Laboratory Study
Journal
J Exp Med (2019)
Country
United States
Reported sample size
—
Source database
PubMed
PMID
31405894
DOI
10.1084/jem.20191098

Abstract (original English)

In this issue of JEM , Rana et al. (https://doi.org/10.1084/jem.20190689) report that adipose tissue multipotent stromal cells (MSCs) provide multifaceted support for adipose tissue-resident ILC2s through contact-mediated proliferation and IL-33-mediated stress-induced activation.

What this study does not prove

  • • This study does not prove SVF is an approved treatment or a replacement for standard care.
  • • This is preclinical work; animal or laboratory results cannot be applied to humans.

Evidence level

Evidence from laboratory and animal studies provides groundwork for understanding mechanisms and potential before human studies continue.

How we grade evidence
Adipose TissueDiabetes Mellitus, Type 2HumansImmunity, InnateLymphocytesStromal Cells

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