Level C· Early human research exploring benefitsRetrospective StudyEurope PMCOpen access

Imaging changes after breast reconstruction with fat grafting - Retrospective study of 90 breast cancer

Noor L., Reeves HR., Kumar D., Alozairi O., Bhaskar P.

Retrospective Study with a reported sample of 90, published in Pak J Med Sci (2016) — summary generated from the PubMed abstract.

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Level C· Early human research exploring benefitsEvidence level of this study

Early human evidence such as case series or small samples is exploring possible benefits.

  • Level A · Stronger Clinical Evidence
  • Level B · Emerging clinical evidence with positive signals
  • Level C · Early human research exploring benefits
  • Level D · Scientific groundwork from lab and animal studies
  • Emerging · Emerging topic under active research
Read the A–D evidence level guide

This page is generated from the PubMed record. The Thai description is an automated summary of bibliographic fields and the abstract, not a full translation, and is not medical advice.

Study type
Retrospective Study
Journal
Pak J Med Sci (2016)
Reported sample size
90
Source database
Europe PMC
PMID
27022335
PMCID
PMC4795895
DOI
10.12669/pjms.321.9460
Citations
7

Abstract (original English)

Objective To evaluate the breast imaging changes after fat grafting and its impact on cancer follow up. Methods This is a retrospective observational study conducted on patients who underwent fat grafting for breast reconstruction. We reviewed mammographic and ultrasound images of patients. Fisher's exact test was used to analyze results. The level of significance was set at P Results A total of ninety patients with breast cancer had fat grafting. Fifty eight patients for defects following post mastectomy reconstruction and 32 for wide local excision defects. The mean follow up was 37.4 months. Benign lumps were identified in 23/90 cases (25 percent). Mammograms were reported as BI-RADS I in 21/32 cases (72 percent) and BI-RADS II in 8/32 cases (28 percent). BI-RADs III score was reported in two patients on further follow up imaging, both were re-classified as BI-RADS II after biopsy. A total of eight patients (8.9 percent) required biopsy. No local recurrences or new cancers were observed in any patients. Conclusion Our study suggests radiological changes after fat grafting are almost always benign with no adverse outcome on cancer follow up.

What this study does not prove

  • • This study does not prove SVF is an approved treatment or a replacement for standard care.
  • • Without an adequate control group, treatment effects cannot be separated from other factors.

Evidence level

Early human evidence such as case series or small samples is exploring possible benefits.

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