Immediate Oncoplastic Breast Reconstruction with Fat Grafting: Preliminary Radiological, Aesthetic, and Patient Satisfaction Outcomes
Har-Shai L., Lagziel T., Grubstein A., Shay T., Ad-El D., Meshulam-Derazon S.
Retrospective Study, published in Aesthetic Plast Surg (2025) — summary generated from the PubMed abstract.
Early human evidence such as case series or small samples is exploring possible benefits.
- Level A · Stronger Clinical Evidence
- Level B · Emerging clinical evidence with positive signals
- Level C · Early human research exploring benefits
- Level D · Scientific groundwork from lab and animal studies
- Emerging · Emerging topic under active research
This page is generated from the PubMed record. The Thai description is an automated summary of bibliographic fields and the abstract, not a full translation, and is not medical advice.
- Study type
- Retrospective Study
- Journal
- Aesthetic Plast Surg (2025)
- Reported sample size
- —
- Source database
- Europe PMC
- PMID
- 40195131
- PMCID
- PMC12423156
- DOI
- 10.1007/s00266-025-04790-3
- Citations
- 1
Abstract (original English)
Introduction Fat grafting is a valuable tool for oncologic breast reconstruction, as it enhances aesthetic outcomes. However, concerns regarding oncologic safety and challenges in postoperative imaging have limited the adoption of immediate oncoplastic breast reconstruction (IOBR) with fat grafting. This approach can reduce the need for additional surgeries, shorten recovery time, improve aesthetics, and help mitigate the adverse effects of adjuvant radiation therapy. This study evaluates postoperative, radiological, aesthetic, and patient-reported outcomes of immediate fat grafting in oncoplastic breast reconstruction following lumpectomy. Methods We conducted a retrospective study of patients undergoing IOBR with immediate fat grafting following lumpectomy (2020-2022). The plastic surgery team performed reconstruction simultaneously with lumpectomy by breast surgeons. Patient satisfaction was assessed using the Breast-Q questionnaire, while expert surgeons evaluated aesthetic outcomes. Lesion characteristics, specimen weight, and postoperative radiation details were recorded. Postoperative breast imaging was reviewed for fat grafting-related abnormalities. Results Fifteen patients were included, with 87% undergoing postoperative radiotherapy. No major complications or readmissions occurred within 30 days. Breast imaging follow-up showed 91.1% had benign post-surgical changes,
What this study does not prove
- • This study does not prove SVF is an approved treatment or a replacement for standard care.
- • Without an adequate control group, treatment effects cannot be separated from other factors.
Evidence level
Early human evidence such as case series or small samples is exploring possible benefits.
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