The Impact of Duration and Force of Centrifugation on Platelet Content and Mass in the Preparation of Platelet-Rich Plasma.
Pensato R., Al-Amer R., La Padula S.
Laboratory Study, published in Aesthetic Plast Surg (2023) — summary generated from the PubMed abstract.
Evidence from laboratory and animal studies provides groundwork for understanding mechanisms and potential before human studies continue.
- Level A · Stronger Clinical Evidence
- Level B · Emerging clinical evidence with positive signals
- Level C · Early human research exploring benefits
- Level D · Scientific groundwork from lab and animal studies
- Emerging · Emerging topic under active research
This page is generated from the PubMed record. The Thai description is an automated summary of bibliographic fields and the abstract, not a full translation, and is not medical advice.
- Study type
- Laboratory Study
- Journal
- Aesthetic Plast Surg (2023)
- Country
- United States
- Reported sample size
- —
- Source database
- PubMed
- PMID
- 37438662
- DOI
- 10.1007/s00266-023-03471-3
- Citations
- 1
Abstract (original English)
The study "Strategies to Improve AFT Volume Retention after Fat Grafting" examines the impact of centrifugation duration and force on platelet-rich plasma (PRP) preparation. PRP, known for its potential in tissue healing and regeneration, lacks standardized protocols. The authors investigate the effects of centrifugation parameters on platelet concentrations and raise concerns about the lack of platelet count specification and characterization in previous studies. The concentration of leukocytes and the platelet-to-leukocyte ratio, as well as the use of non-activated platelets, are also discussed. Challenges in administering PRP gel and the morphological changes of activated platelets are noted. Further analysis is needed for reliable conclusions on PRP applications.Level of Evidence V This journal requires that authors assign a level of evidence to each article. For a full description of these evidence-based medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266 .
What this study does not prove
- • This study does not prove SVF is an approved treatment or a replacement for standard care.
- • This is preclinical work; animal or laboratory results cannot be applied to humans.
Evidence level
Evidence from laboratory and animal studies provides groundwork for understanding mechanisms and potential before human studies continue.
How we grade evidenceBrowse all related research
Filter the research library by this study's title keywords, author, or publication year.