Level D· Scientific groundwork from lab and animal studiesAnimal StudyPubMed

[Influence of transplantation of autogenic mezenhymal stem cells from the fatty tissues on osseogenic process (experimental research)].

Orlov AA., Saburina IN., Sisoev SD., Grigorian AD.

Animal Study on Face & Skin, published in Patol Fiziol Eksp Ter (2014) — summary generated from the PubMed abstract.

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Level D· Scientific groundwork from lab and animal studiesEvidence level of this study

Evidence from laboratory and animal studies provides groundwork for understanding mechanisms and potential before human studies continue.

  • Level A · Stronger Clinical Evidence
  • Level B · Emerging clinical evidence with positive signals
  • Level C · Early human research exploring benefits
  • Level D · Scientific groundwork from lab and animal studies
  • Emerging · Emerging topic under active research
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This page is generated from the PubMed record. The Thai description is an automated summary of bibliographic fields and the abstract, not a full translation, and is not medical advice.

Study type
Animal Study
Journal
Patol Fiziol Eksp Ter (2014)
Country
Russia (Federation)
Reported sample size
—
Source database
PubMed
PMID
25051675

Abstract (original English)

In experiments on 48 rats of line Wistar, divided at 2 groups (first--basic group and 2-d group--group of comparison) through the use of morphological method was researched influence of mesenchymal stem cells (MSC) inoculated in the area of autogenic bone graft from tibia fixed at the surface of the jaw. The animals of group of comparison didn't get MSC. Time frames of watching: 21, 60, 120 and 180 days, 6 rats on the point of experiment in either of the two of the group. Data of this research had shown the intensification of bone formation process in the basic group of experiment under the action of the inoculation of autogenic MSC from adipose tissue, and as consequence of it, in eventual, merge of bone formations in a single entity.

What this study does not prove

  • • This study does not prove SVF is an approved treatment or a replacement for standard care.
  • • This is preclinical work; animal or laboratory results cannot be applied to humans.

Evidence level

Evidence from laboratory and animal studies provides groundwork for understanding mechanisms and potential before human studies continue.

How we grade evidence
Adipose TissueAnimalsMesenchymal Stem Cell TransplantationMesenchymal Stem CellsOrthognathic Surgical ProceduresOsteogenesisRatsRats, WistarTibiaTransplantation, Autologous

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