Innovative Applications of Nanomaterials in the Diagnosis and Treatment of Ocular Diseases: Targeted Delivery, Intelligent Therapy, Diagnostic Breakthroughs, and Synergistic Strategies with Stem Cells and Biomaterials
Su G., Xu W.
Narrative Review, published in Int J Nanomedicine (2026) — summary generated from the PubMed abstract.
Evidence from laboratory and animal studies provides groundwork for understanding mechanisms and potential before human studies continue.
- Level A · Stronger Clinical Evidence
- Level B · Emerging clinical evidence with positive signals
- Level C · Early human research exploring benefits
- Level D · Scientific groundwork from lab and animal studies
- Emerging · Emerging topic under active research
This page is generated from the PubMed record. The Thai description is an automated summary of bibliographic fields and the abstract, not a full translation, and is not medical advice.
- Study type
- Narrative Review
- Journal
- Int J Nanomedicine (2026)
- Reported sample size
- —
- Source database
- Europe PMC
- PMID
- 42005706
- PMCID
- PMC13091631
- DOI
- 10.2147/ijn.s577320
Abstract (original English)
The complex physiological structures and multiple biological barriers of the eye pose significant challenges to drug delivery, resulting in poor absorption and limited therapeutic efficacy of conventional treatments. In this review, nanomaterials with their distinctive physicochemical properties and biocompatibility have emerged as essential tools in the diagnosis and treatment of ocular diseases. We summarized the latest advancements in the application of nanomaterials for targeted drug delivery, smart therapeutic strategies, and early diagnostic technologies specific to ocular diseases. This work provides a comprehensive analysis of the design concepts, biocompatibility, and controlled release mechanisms of various nanocarriers. It also examines their therapeutic potential in inflammatory eye diseases and retinal degenerative conditions. Additionally, the advantages of naturally derived nanomaterials and their potential applications in ocular drug delivery systems are explored. Furthermore, the role of stem cell therapies in enhancing tissue regeneration and supporting treatment efficacy is discussed. In the future, this review discusses the integration of nanotechnology with artificial intelligence to advance the development of precision medicine in ophthalmology by elucidating their synergistic roles. The aim of this article is to provide researchers and clinicians with a s
What this study does not prove
- • This study does not prove SVF is an approved treatment or a replacement for standard care.
- • This is a narrative review: it collects no new patient data and does not systematically appraise evidence quality.
Evidence level
Evidence from laboratory and animal studies provides groundwork for understanding mechanisms and potential before human studies continue.
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