Intelligent multimodal-energy-driven piezoelectric antibacterial platforms: From structural control to system-level diagnosis
Liu J., Li J., Sun H., Seo J., Zhang Y., Yu Y.
Narrative Review, published in Mater Today Bio (2026) — summary generated from the PubMed abstract.
Evidence from laboratory and animal studies provides groundwork for understanding mechanisms and potential before human studies continue.
- Level A · Stronger Clinical Evidence
- Level B · Emerging clinical evidence with positive signals
- Level C · Early human research exploring benefits
- Level D · Scientific groundwork from lab and animal studies
- Emerging · Emerging topic under active research
This page is generated from the PubMed record. The Thai description is an automated summary of bibliographic fields and the abstract, not a full translation, and is not medical advice.
- Study type
- Narrative Review
- Journal
- Mater Today Bio (2026)
- Reported sample size
- —
- Source database
- Europe PMC
- PMID
- 42293387
- PMCID
- PMC13253188
- DOI
- 10.1016/j.mtbio.2026.103299
Abstract (original English)
Piezocatalysis offers a non-antibiotic, physical-chemical approach to address the challenge of bacterial infection resistance, but its reliance on single energy sources and empirical design limits its potential. This review focuses on intelligent piezoelectric antibacterial platforms powered by multimodal energy and enhanced by artificial intelligence, systematically summarizing the latest research progress in the field. First, based on an in-depth analysis of the limitations of traditional antibacterial strategies, the evolutionary trajectory of piezoelectric technology from single-energy to multimodal synergistic driving is clarified. Second, we systematically explain the piezocatalytic antibacterial mechanism and reveal its synergistic enhancement with other antibacterial components under multiphysical fields, highlighting their comprehensive advantages in improving antibacterial efficacy and achieving precise spatiotemporal control. Furthermore, the synergistic regulatory effects of key structural parameters on the piezoelectric properties and antibacterial activity of materials are thoroughly analyzed. Additionally, typical application cases of such intelligent platforms in cutting-edge scenarios, such as smart wound management, functional anti-infection implant coatings, and precise intervention for localized infections in the lungs and oral cavity, are systematically rev
What this study does not prove
- • This study does not prove SVF is an approved treatment or a replacement for standard care.
- • This is a narrative review: it collects no new patient data and does not systematically appraise evidence quality.
Evidence level
Evidence from laboratory and animal studies provides groundwork for understanding mechanisms and potential before human studies continue.
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