Intramuscular and Subcutaneous Lipofilling in Mastopexy: Technical Considerations and Clinical Outcomes.
Bruno A., Foti R.
Retrospective Study with a reported sample of 36, published in Aesthetic Plast Surg (2026) — summary generated from the PubMed abstract.
Early human evidence such as case series or small samples is exploring possible benefits.
- Level A · Stronger Clinical Evidence
- Level B · Emerging clinical evidence with positive signals
- Level C · Early human research exploring benefits
- Level D · Scientific groundwork from lab and animal studies
- Emerging · Emerging topic under active research
This page is generated from the PubMed record. The Thai description is an automated summary of bibliographic fields and the abstract, not a full translation, and is not medical advice.
- Study type
- Retrospective Study
- Journal
- Aesthetic Plast Surg (2026)
- Country
- United States
- Reported sample size
- 36
- Source database
- PubMed
- PMID
- 41944876
- DOI
- 10.1007/s00266-026-05823-1
Abstract (original English)
Background Mastopexy remains the gold standard for correcting breast ptosis, yet persistent limitations include insufficient restoration of upper pole fullness and lack of long-term projection. While prosthetic augmentation addresses these concerns, implants are associated with complications and growing patient reluctance. Autologous fat transfer represents a biocompatible alternative, with regenerative potential and proven safety. However, systematic approaches to layered fat grafting during mastopexy remain underexplored. Methods We retrospectively reviewed 36 patients (mean age 38.5 years) who underwent mastopexy combined with intramuscular and subcutaneous lipofilling between June 2023 and June 2024. Fat was harvested via low-pressure aspiration, processed by decantation, and injected using micro-aliquot retrograde technique. Intramuscular placement targeted durable upper pole projection, while subcutaneous grafting refined contour and softness. Outcomes were assessed through standardized photography, clinical examination, complication monitoring, and patient-reported satisfaction using the BREAST-Q questionnaire. Results Mean grafted volumes were 210 cc intramuscularly and 115 cc subcutaneously per breast. No intraoperative complications occurred. Minor delayed healing (8.3%) and small oil cysts (8.3%) were managed conservatively. No cases of infection, fat necrosis requir
What this study does not prove
- • This study does not prove SVF is an approved treatment or a replacement for standard care.
- • Without an adequate control group, treatment effects cannot be separated from other factors.
Evidence level
Early human evidence such as case series or small samples is exploring possible benefits.
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