SVF
Level D· Preclinical EvidenceAnimal Study

Laparoscopic adipose-derived stem cell harvest technique with bipolar sealing device: Outcome in 12 dogs.

Buote NJ.

Animal Study with a reported sample of 12 on Osteoarthritis, published in Vet Med Sci (2022) — summary generated from the PubMed abstract.

This page is generated from the PubMed record. The Thai description is an automated summary of bibliographic fields and the abstract, not a full translation, and is not medical advice.

Study type
Animal Study
Journal
Vet Med Sci (2022)
Country
England
Reported sample size
12
PMID
35537084
DOI
10.1002/vms3.816

Abstract (original English)

This study aimed to describe the technique and clinical outcomes in dogs undergoing Laparoscopic Adipose-Derived Stem Cell Harvest via bipolar sealing device (LADSCHB) for degenerative orthopaedic and neurologic disease. Descriptive retrospective case series. Eleven dogs with orthopaedic disease and one dog with degenerative spinal disease were enrolled in the study. Medical records of dogs undergoing LADSCHB were reviewed for signalment, weight, reason for the procedure, anaesthesia time, surgery time, other procedures performed, post-operative pain protocols, incision size, amount of adipose tissue collected, number of viable cells collected, days to discharge, short-term complications, and owner satisfaction. The median weight of the population was 34.2 kg (range 9.2-62 kg), the median surgery time was 39 min (range 15-45 min), mean incision length was 2.5 cm, the median amount of adipose collected was 60 g, and the median number of viable stem cells was 21 million cells. Conversion to open laparotomy was not needed. The most common reason for the harvest was osteoarthritis of the elbow (8/12 cases). Nine cases had other procedures performed at the same time as the harvest. No complications were noted during the procedure or within the post-operative period. All owners surveyed were satisfied with the laparoscopic harvest procedure. LADSCHB was technically feasible, producti

What this study does not prove

  • • This study does not prove SVF is an approved treatment or a replacement for standard care.
  • • This is preclinical work; animal or laboratory results cannot be applied to humans.

Evidence level

Evidence comes from animal or laboratory studies and has not been confirmed in humans.

How we grade evidence
Adipose TissueAnimalsDog DiseasesDogsLaparoscopyRetrospective StudiesStem Cells
Arm & ElbowBack & SpineOsteoarthritis
View on PubMedDOI

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