The Lipo-DIEP Flap Breast Reconstruction: A Valuable Innovation for Maximizing Abdominal Tissue Volume
Longo B., D'Orsi G., Farcomeni A., Giacalone M., Gagliano E., Vannucchi L.
Prospective Study, published in Plast Reconstr Surg Glob Open (2025) — summary generated from the PubMed abstract.
Early human evidence such as case series or small samples is exploring possible benefits.
- Level A · Stronger Clinical Evidence
- Level B · Emerging clinical evidence with positive signals
- Level C · Early human research exploring benefits
- Level D · Scientific groundwork from lab and animal studies
- Emerging · Emerging topic under active research
This page is generated from the PubMed record. The Thai description is an automated summary of bibliographic fields and the abstract, not a full translation, and is not medical advice.
- Study type
- Prospective Study
- Journal
- Plast Reconstr Surg Glob Open (2025)
- Reported sample size
- —
- Source database
- Europe PMC
- PMID
- 39830442
- PMCID
- PMC11741219
- DOI
- 10.1097/gox.0000000000006445
- Citations
- 4
Abstract (original English)
Background The deep inferior epigastric perforator (DIEP) flap is universally considered the gold standard technique for breast reconstruction (BR), though it cannot always be proposed to patients with insufficient donor-site volume. We explore the efficacy of autologous fat transfer (AFT) of the Holm abdomen zone IV in the retropectoral plane during DIEP flap reconstruction (lipo-DIEP flap), to enhance the volume provided by the abdominal donor site in patients with low body mass index (BMI). Methods We prospectively enrolled patients with BMI less than 25 kg/m 2 and candidates for lipo-DIEP flap BR (group A) comparing them with a control group (group B) undergoing traditional DIEP flap BR with the same characteristics of the first group (BMI 2 ). Patients belonging to group A underwent magnetic resonance imaging preoperatively and 6 months after the BR, evaluating the adipose tissue volume retained in the retropectoral space. Results A total of 40 breasts were included in the study. The 2 groups were homogeneous regarding the collected variables, except for mean delayed AFT sessions (0.25 versus 0.95; P = 0.00094). The average volume of retropectoral AFT was 116.25 mL (SD 31.36). Six months after the procedure, the mean retropectoral fat volume calculated through magnetic resonance imaging was 48.64 mL (SD 14.15), whereas the mean graft integration rate was 45.98% (range, 30.
What this study does not prove
- • This study does not prove SVF is an approved treatment or a replacement for standard care.
Evidence level
Early human evidence such as case series or small samples is exploring possible benefits.
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