The Liquid Genioplasty: Different Techniques Compared
Goisis M., Veronese S., Kasilovska P., Malakhova O., Hirache K., Nicoletti MM.
Retrospective Study with a reported sample of 225 on Face & Skin, published in Aesthetic Plast Surg (2026) — summary generated from the PubMed abstract.
Early human evidence such as case series or small samples is exploring possible benefits.
- Level A · Stronger Clinical Evidence
- Level B · Emerging clinical evidence with positive signals
- Level C · Early human research exploring benefits
- Level D · Scientific groundwork from lab and animal studies
- Emerging · Emerging topic under active research
This page is generated from the PubMed record. The Thai description is an automated summary of bibliographic fields and the abstract, not a full translation, and is not medical advice.
- Study type
- Retrospective Study
- Journal
- Aesthetic Plast Surg (2026)
- Reported sample size
- 225
- Source database
- Europe PMC
- PMID
- 41644820
- PMCID
- PMC13102854
- DOI
- 10.1007/s00266-025-05557-6
Abstract (original English)
Background Non-surgical genioplasty is one of the best choices in cases of chin retrusion, and it represents a solution for the aesthetic amelioration of facial profile. Recent concerns arose about the risk of bone resorption and vascular occlusion. Different procedures and products may lead to different results. This study reports the experience of a single facial plastic surgeon (M.G.) using non-surgical techniques to fill the chin. Methods This retrospective study assesses 225 patients injected from January 2019 through March 2024 in private clinics in Milan (Italy), London (UK), and Dubai (UAE). Forty-five patients were injected with hyaluronic acid (Genefill DX 1x1 ml, BioScience GmbH, Dümmer, Germany), 90 underwent a lipofilling procedure, and 90 underwent a Dermgraft procedure, that is, a personalized lipofilling, modified by the main author. Half of the last 180 patients underwent shock waves before fat harvesting. Patients were followed up for 12 months, and facial angles and satisfaction data were analyzed. Three experts scored the results over time. Results After all the treatments, facial angles were corrected, but the maintenance of the results varied for the different treatments. Notably, at 3 months, the levels of satisfaction were higher for the HA filler treatment, while at 1 year, the levels of satisfaction were very high for the Dermgraft. Conclusions Liquid
What this study does not prove
- • This study does not prove SVF is an approved treatment or a replacement for standard care.
- • Without an adequate control group, treatment effects cannot be separated from other factors.
Evidence level
Early human evidence such as case series or small samples is exploring possible benefits.
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