Magnetic nanomaterials for hyperthermia-based therapy and controlled drug delivery
Chen Y., Sun H., Li Y., Han X., Yang Y., Chen Z.
Narrative Review, published in Bioact Mater (2025) — summary generated from the PubMed abstract.
Evidence from laboratory and animal studies provides groundwork for understanding mechanisms and potential before human studies continue.
- Level A · Stronger Clinical Evidence
- Level B · Emerging clinical evidence with positive signals
- Level C · Early human research exploring benefits
- Level D · Scientific groundwork from lab and animal studies
- Emerging · Emerging topic under active research
This page is generated from the PubMed record. The Thai description is an automated summary of bibliographic fields and the abstract, not a full translation, and is not medical advice.
- Study type
- Narrative Review
- Journal
- Bioact Mater (2025)
- Reported sample size
- —
- Source database
- Europe PMC
- PMID
- 40761549
- PMCID
- PMC12320187
- DOI
- 10.1016/j.bioactmat.2025.07.033
- Citations
- 19
Abstract (original English)
As an innovative physiotherapeutic approach, magnetic hyperthermia therapy (MHT) has unique advantages including minimal invasiveness, precise temperature control, and deep tissue penetration capabilities. It offers unparalleled control over heating areas and temperatures, boasts high efficiency, and results in excellent tissue penetration, while remaining independent of biological tissues. With vast potential in biomedical applications ranging from antitumor therapy to thrombus dissolution, MHT harnesses magnetic nanoparticles (MNPs) to convert magnetic energy into thermal energy under an alternating magnetic field (AMF), thereby achieving therapeutic effects. Advanced magnetic nanocomposite platforms based on magnetic nanoparticles can avoid various risks associated with traditional tools, achieving precise, on-demand, or continuous targeted drug delivery and release through multiple approaches. The potential clinical applications of magnetic hyperthermia therapy are being progressively developed. The present article presents an exhaustive review of the research progress in magnetic hyperthermia therapy. Initially, the overall landscape of MHT was outlined, including physical heat generation mechanisms, types of magnetic nanoparticles and conductive nonmagnetic materials, strategies to increase the thermal efficiency of MNPs, and experimental evidence and research progress on
What this study does not prove
- • This study does not prove SVF is an approved treatment or a replacement for standard care.
- • This is a narrative review: it collects no new patient data and does not systematically appraise evidence quality.
Evidence level
Evidence from laboratory and animal studies provides groundwork for understanding mechanisms and potential before human studies continue.
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