Level C· Early human research exploring benefitsRetrospective StudyEurope PMCOpen access

Management of Permanent Filler Complications Using Deep-Plane Facelift and Temporoparietal Fascial Flap Reconstruction: A Retrospective Study

Ghoraba S., Loucas M., Loucas R.

Retrospective Study with a reported sample of 160 on Face & Skin, published in Aesthet Surg J Open Forum (2025) — summary generated from the PubMed abstract.

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Level C· Early human research exploring benefitsEvidence level of this study

Early human evidence such as case series or small samples is exploring possible benefits.

  • Level A · Stronger Clinical Evidence
  • Level B · Emerging clinical evidence with positive signals
  • Level C · Early human research exploring benefits
  • Level D · Scientific groundwork from lab and animal studies
  • Emerging · Emerging topic under active research
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This page is generated from the PubMed record. The Thai description is an automated summary of bibliographic fields and the abstract, not a full translation, and is not medical advice.

Study type
Retrospective Study
Journal
Aesthet Surg J Open Forum (2025)
Reported sample size
160
Source database
Europe PMC
PMID
41376670
PMCID
PMC12686812
DOI
10.1093/asjof/ojaf106

Abstract (original English)

Background Permanent fillers can lead to long-term complications, including granulomas, infections, and migration. Their removal often causes significant facial defects, posing challenges in reconstructive surgery. Objectives The authors of this study aim to evaluate the clinical outcomes of deep-plane facelifts combined with temporoparietal fascial flap (TPFF) reconstruction in managing complications and restoring aesthetics following permanent filler removal. Methods This retrospective study included 160 patients who underwent deep-plane facelifts with permanent filler removal and TPFF reconstruction between 2014 and 2022. Those with unrealistic expectations, BMI >30, a recent infection (≤3 months), or severe malar edema were excluded. The average follow-up period was 16 months (range, 6-68 months). Results Of 160 patients (149 females, 11 males; mean age 48 ± 8.4 years), 131 (82%) completed follow-up. The complication rate was 22%, including transient swelling and bruising (15%), minor infections (4%), and hematomas (3%). Psychological outcomes improved significantly, with increased self-esteem and social interaction scores and reduced anxiety and depression levels. Hospital stays averaged 32 h (range, 24-48 h). Conclusions TPFF reconstruction during deep-plane facelifts is a reliable approach for addressing complications and defects following permanent filler removal. This

What this study does not prove

  • • This study does not prove SVF is an approved treatment or a replacement for standard care.
  • • Without an adequate control group, treatment effects cannot be separated from other factors.

Evidence level

Early human evidence such as case series or small samples is exploring possible benefits.

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