Level C· Early Human Research
Adipose-derived stromal vascular fraction (SVF) for the treatment of androgenic alopecia (AGA): a systematic review
Mantovani G.P., Marra C., De Maria F., De Santis G.
Screened 140 articles and retained nine; all reported a statistically significant increase in hair density with no serious adverse events.
- Study type
- Systematic Review
- Journal
- Acta Bio-Medica (2023)
- Country
- Italy
- Sample size
- —
- Follow-up
- Varied across included studies
- PMID
- 37850761
- DOI
- 10.23750/abm.v94i5.15069
What was studied
Effects of SVF and adipose stem cells on androgenetic alopecia.
Methods
- • Literature search in October 2022 with predefined inclusion criteria.
Key findings
- • All studies reported increased hair density, some also increased hair diameter.
- • Combining SVF with standard medical therapy appeared advantageous.
- • No standardised protocol was found across studies.
Limitations
- • Few studies, most with small samples.
- • Many studies lacked appropriate controls.
What this study does not prove
- • This study does not prove SVF is an approved treatment or a replacement for standard care.
- • Limited follow-up cannot indicate long-term outcomes.
Clinical interpretation
Consistently positive direction, but non-standard protocols make results hard to compare.
Evidence level: Early Human Research