Level C· Early human research exploring benefits
Adipose-derived stromal vascular fraction (SVF) for the treatment of androgenic alopecia (AGA): a systematic review
Mantovani G.P., Marra C., De Maria F., De Santis G.
Screened 140 articles and retained nine; all reported a statistically significant increase in hair density with no serious adverse events.
Level C· Early human research exploring benefitsEvidence level of this study
Early human evidence such as case series or small samples is exploring possible benefits.
- Level A · Stronger Clinical Evidence
- Level B · Emerging clinical evidence with positive signals
- Level C · Early human research exploring benefits
- Level D · Scientific groundwork from lab and animal studies
- Emerging · Emerging topic under active research
- Study type
- Systematic Review
- Journal
- Acta Bio-Medica (2023)
- Country
- Italy
- Sample size
- —
- Follow-up
- Varied across included studies
- PMID
- 37850761
- DOI
- 10.23750/abm.v94i5.15069
What was studied
Effects of SVF and adipose stem cells on androgenetic alopecia.
Methods
- • Literature search in October 2022 with predefined inclusion criteria.
Key findings
- • All studies reported increased hair density, some also increased hair diameter.
- • Combining SVF with standard medical therapy appeared advantageous.
- • No standardised protocol was found across studies.
Limitations
- • Few studies, most with small samples.
- • Many studies lacked appropriate controls.
What this study does not prove
- • This study does not prove SVF is an approved treatment or a replacement for standard care.
- • Limited follow-up cannot indicate long-term outcomes.
Clinical interpretation
Consistently positive direction, but non-standard protocols make results hard to compare.
Evidence level: Early human research exploring benefits