Mechanisms and applications of mesenchymal stem cell exosomes in enhancing fertility
Wang Y., Wang R., Zhao Y., Han N., Han X., Shi T.
Narrative Review, published in Stem Cell Res Ther (2025) — summary generated from the PubMed abstract.
Evidence from laboratory and animal studies provides groundwork for understanding mechanisms and potential before human studies continue.
- Level A · Stronger Clinical Evidence
- Level B · Emerging clinical evidence with positive signals
- Level C · Early human research exploring benefits
- Level D · Scientific groundwork from lab and animal studies
- Emerging · Emerging topic under active research
This page is generated from the PubMed record. The Thai description is an automated summary of bibliographic fields and the abstract, not a full translation, and is not medical advice.
- Study type
- Narrative Review
- Journal
- Stem Cell Res Ther (2025)
- Reported sample size
- —
- Source database
- Europe PMC
- PMID
- 41153022
- PMCID
- PMC12570428
- DOI
- 10.1186/s13287-025-04729-0
Abstract (original English)
Infertility is an increasingly prevalent global health issue affecting millions of couples. It can arise from various factors, including hormonal imbalances, reproductive disorders, and anatomical abnormalities. While numerous treatment options exist, such as assisted reproductive technologies, these approaches often entail significant costs and have limited success rates. In this paper, we review the role of mesenchymal stem cell exosomes (MSC-Exos) in the treatment of infertility, with a particular focus on their potential to enhance fertility. We herein aimed to integrate the latest research progress in this field and emphasize the importance of MSC-Exos as a potential treatment for infertility.
What this study does not prove
- • This study does not prove SVF is an approved treatment or a replacement for standard care.
- • This is a narrative review: it collects no new patient data and does not systematically appraise evidence quality.
Evidence level
Evidence from laboratory and animal studies provides groundwork for understanding mechanisms and potential before human studies continue.
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