Morphology and size of stem cells from mouse and whale: observational study.
Hoogduijn MJ., van den Beukel JC., Wiersma LC., Ijzer J.
Animal Study, published in BMJ (2013) — summary generated from the PubMed abstract.
Evidence from laboratory and animal studies provides groundwork for understanding mechanisms and potential before human studies continue.
- Level A · Stronger Clinical Evidence
- Level B · Emerging clinical evidence with positive signals
- Level C · Early human research exploring benefits
- Level D · Scientific groundwork from lab and animal studies
- Emerging · Emerging topic under active research
This page is generated from the PubMed record. The Thai description is an automated summary of bibliographic fields and the abstract, not a full translation, and is not medical advice.
- Study type
- Animal Study
- Journal
- BMJ (2013)
- Country
- England
- Reported sample size
- —
- Source database
- PubMed
- PMID
- 24336001
- DOI
- 10.1136/bmj.f6833
Abstract (original English)
To compare the morphology and size of stem cells from two mammals of noticeably different body size. Observational study. The Netherlands. A humpback whale (Megaptera novaeangliae) and a laboratory mouse (Mus musculus). Morphology and size of mesenchymal stem cells from adipose tissue. Morphologically, mesenchymal stem cells of the mouse and whale are indistinguishable. The average diameter of 50 mesenchymal stem cells from the mouse was 28 (SD 0.86) µm and 50 from the whale was 29 (SD 0.71) µm. The difference in cell size between the species was not statistically significant. Although the difference in bodyweight between the species is close to two million-fold, the mesenchymal stem cells of each were of similar size. The mesenchymal stem cells of whales and mice are alike, in both morphology and size.
What this study does not prove
- • This study does not prove SVF is an approved treatment or a replacement for standard care.
- • This is preclinical work; animal or laboratory results cannot be applied to humans.
Evidence level
Evidence from laboratory and animal studies provides groundwork for understanding mechanisms and potential before human studies continue.
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