SVF
Level D· Scientific groundwork from lab and animal studiesLaboratory StudyPubMed

Nanostructured Capsules for Cartilage Tissue Engineering.

Correia CR., Reis RL., Mano JF.

Laboratory Study on Cartilage Damage, published in Methods Mol Biol (2015) — summary generated from the PubMed abstract.

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Level D· Scientific groundwork from lab and animal studiesEvidence level of this study

Evidence from laboratory and animal studies provides groundwork for understanding mechanisms and potential before human studies continue.

  • Level A · Stronger Clinical Evidence
  • Level B · Emerging clinical evidence with positive signals
  • Level C · Early human research exploring benefits
  • Level D · Scientific groundwork from lab and animal studies
  • Emerging · Emerging topic under active research
Read the A–D evidence level guide

This page is generated from the PubMed record. The Thai description is an automated summary of bibliographic fields and the abstract, not a full translation, and is not medical advice.

Study type
Laboratory Study
Journal
Methods Mol Biol (2015)
Country
United States
Reported sample size
—
Source database
PubMed
PMID
26445839
DOI
10.1007/978-1-4939-2938-2_13
Citations
6

Abstract (original English)

Polymeric multilayered capsules (PMCs) have found great applicability in bioencapsulation, an evolving branch of tissue engineering and regenerative medicine. Here, we describe the production of hierarchical PMCs composed by an external multilayered membrane by layer-by-layer assembly of poly(L-lysine), alginate, and chitosan. The core of the PMCs is liquified and encapsulates human adipose stem cells and surface-functionalized collagen II-TGF-β3 poly(L-lactic acid) microparticles for cartilage tissue engineering.

What this study does not prove

  • • This study does not prove SVF is an approved treatment or a replacement for standard care.
  • • This is preclinical work; animal or laboratory results cannot be applied to humans.

Evidence level

Evidence from laboratory and animal studies provides groundwork for understanding mechanisms and potential before human studies continue.

How we grade evidence
AlginatesCartilageCell Culture TechniquesCell DifferentiationCells, CulturedChitosanChondrocytesChondrogenesisCollagen Type IIGlucuronic Acid
Face & SkinCartilage Damage
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