Level C· Early human research exploring benefitsProspective StudyEurope PMCOpen access

Nasal Reconstruction in Granulomatosis with Polyangiitis Using an L-shaped Cartilage Strut Graft

Czimbalmos LI., Bere Z., Kovacs L., Kovacs P., Rovo L., Vass G.

Prospective Study, published in Aesthetic Plast Surg (2025) — summary generated from the PubMed abstract.

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Level C· Early human research exploring benefitsEvidence level of this study

Early human evidence such as case series or small samples is exploring possible benefits.

  • Level A · Stronger Clinical Evidence
  • Level B · Emerging clinical evidence with positive signals
  • Level C · Early human research exploring benefits
  • Level D · Scientific groundwork from lab and animal studies
  • Emerging · Emerging topic under active research
Read the A–D evidence level guide

This page is generated from the PubMed record. The Thai description is an automated summary of bibliographic fields and the abstract, not a full translation, and is not medical advice.

Study type
Prospective Study
Journal
Aesthetic Plast Surg (2025)
Reported sample size
—
Source database
Europe PMC
PMID
40394317
PMCID
PMC12594648
DOI
10.1007/s00266-025-04892-y

Abstract (original English)

Methodology Patients exhibited progressive saddle nose deformity as a result of GPA. To reconstruct the nose, a single-stage open rhinoplasty was conducted involving the placement of an independent L-shaped costal cartilage implant. Graft formation and fixation were performed according to the author-developed method. Results From 2012 to 2023, seven patients with severe saddle nose deformity underwent implantation of modified L-shaped costal cartilage strut grafts. Except for one complicated case, all patients reported satisfaction with the surgical outcomes. Conclusions In this study, the visual appeal of the nose and the respiratory capabilities of the patients improved significantly. The L-shaped costal cartilage strut graft is an effective technique for saddle nose deformity correction. This technique provides excellent outcomes, including improved nasal function and aesthetics. Further studies with a larger sample size are needed to confirm these findings. Level of evidence ii This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266 .

What this study does not prove

  • • This study does not prove SVF is an approved treatment or a replacement for standard care.

Evidence level

Early human evidence such as case series or small samples is exploring possible benefits.

How we grade evidence
HumansNose Deformities, AcquiredTreatment OutcomeRhinoplastyRetrospective StudiesFollow-Up StudiesEstheticsAdultMiddle AgedPatient Satisfaction

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