Level C· Early human research exploring benefitsRetrospective StudyEurope PMCOpen access

Natural Reconstruction: A Comprehensive Standardized Operating Procedure for Restoring Eyebrow Loss Due to Scarring

Chen J., Qu Q., Ye K., Fan Z., Wang J., Liu B.

Retrospective Study with a reported sample of 167 on Scar, published in Plast Reconstr Surg (2022) — summary generated from the PubMed abstract.

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Level C· Early human research exploring benefitsEvidence level of this study

Early human evidence such as case series or small samples is exploring possible benefits.

  • Level A · Stronger Clinical Evidence
  • Level B · Emerging clinical evidence with positive signals
  • Level C · Early human research exploring benefits
  • Level D · Scientific groundwork from lab and animal studies
  • Emerging · Emerging topic under active research
Read the A–D evidence level guide

This page is generated from the PubMed record. The Thai description is an automated summary of bibliographic fields and the abstract, not a full translation, and is not medical advice.

Study type
Retrospective Study
Journal
Plast Reconstr Surg (2022)
Reported sample size
167
Source database
Europe PMC
PMID
35939643
PMCID
PMC9512239
DOI
10.1097/prs.0000000000009564
Citations
5

Abstract (original English)

Background Scarring that results in eyebrow loss is a cosmetic problem that can result in severe psychological distress. Although hair transplantation is increasingly used for eyebrow restoration, graft loss may occur, preventing achievement of desired results. Single-hair follicle transplantation, however, may be effective. The authors describe outcomes of a standardized method of eyebrow reconstruction, involving single-hair follicle transplantation combined with follicular unit extraction, in patients with absent eyebrows because of scarring. Methods This study was approved by the institutional ethics committee of Nanfang Hospital and all patients provided written informed consent before surgery. The medical records of patients who underwent eyebrow reconstruction from 2012 to 2019 for eyebrow loss caused by scar formation were reviewed retrospectively. Outcomes evaluated included satisfaction, graft survival rate, and long-term complications. A nine-step standardized operating procedure was established for eyebrow reconstruction in patients with eyebrow absence attributable to scarring. Results During the study period, 167 patients (205 eyebrows) underwent eyebrow reconstruction. Following the first stage of reconstruction, 95 percent of patients were highly satisfied with the density and natural appearance of their eyebrows. The average graft survival rate was 85 percent (

What this study does not prove

  • • This study does not prove SVF is an approved treatment or a replacement for standard care.
  • • Without an adequate control group, treatment effects cannot be separated from other factors.

Evidence level

Early human evidence such as case series or small samples is exploring possible benefits.

How we grade evidence
EyebrowsCicatrixHair FollicleHumansSkin TransplantationRetrospective Studies

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