Level B· Emerging clinical evidence with positive signalsRandomized Controlled TrialEurope PMC

Neurorestoration after stroke

Azad TD., Veeravagu A., Steinberg GK.

Randomized Controlled Trial on Stroke Research, published in Neurosurg Focus (2016) — summary generated from the PubMed abstract.

Open my reading list
Level B· Emerging clinical evidence with positive signalsEvidence level of this study

Several human studies show positive signals, while research methods and sample sizes continue to develop.

  • Level A · Stronger Clinical Evidence
  • Level B · Emerging clinical evidence with positive signals
  • Level C · Early human research exploring benefits
  • Level D · Scientific groundwork from lab and animal studies
  • Emerging · Emerging topic under active research
Read the A–D evidence level guide

This page is generated from the PubMed record. The Thai description is an automated summary of bibliographic fields and the abstract, not a full translation, and is not medical advice.

Study type
Randomized Controlled Trial
Journal
Neurosurg Focus (2016)
Reported sample size
—
Source database
Europe PMC
PMID
27132523
PMCID
PMC4916840
DOI
10.3171/2016.2.focus15637
Citations
71

Abstract (original English)

Recent advancements in stem cell biology and neuromodulation have ushered in a battery of new neurorestorative therapies for ischemic stroke. While the understanding of stroke pathophysiology has matured, the ability to restore patients' quality of life remains inadequate. New therapeutic approaches, including cell transplantation and neurostimulation, focus on reestablishing the circuits disrupted by ischemia through multidimensional mechanisms to improve neuroplasticity and remodeling. The authors provide a broad overview of stroke pathophysiology and existing therapies to highlight the scientific and clinical implications of neurorestorative therapies for stroke.

What this study does not prove

  • • This study does not prove SVF is an approved treatment or a replacement for standard care.

Evidence level

Several human studies show positive signals, while research methods and sample sizes continue to develop.

How we grade evidence
AnimalsHumansElectric Stimulation TherapyCell TransplantationRecovery of FunctionNeuronal PlasticityStroke

Browse all related research

Filter the research library by this study's title keywords, author, or publication year.

Related research