[New ultrastructural characteristics of the bone marrow stromal cells in patients with aplastic anemia].
Ponomarenko VM., Blinova TS., Shilova ER., Ovodov NG., Rugal' VI.
Prospective Study, published in Gematol Transfuziol (1993) — summary generated from the PubMed abstract.
Early human evidence such as case series or small samples is exploring possible benefits.
- Level A · Stronger Clinical Evidence
- Level B · Emerging clinical evidence with positive signals
- Level C · Early human research exploring benefits
- Level D · Scientific groundwork from lab and animal studies
- Emerging · Emerging topic under active research
This page is generated from the PubMed record. The Thai description is an automated summary of bibliographic fields and the abstract, not a full translation, and is not medical advice.
- Study type
- Prospective Study
- Journal
- Gematol Transfuziol (1993)
- Country
- Russia (Federation)
- Reported sample size
- —
- Source database
- PubMed
- PMID
- 8020695
Abstract (original English)
Unlike hemopoietic cell, stromal cells of aplastic anemia patients' bone marrow undergo pathological shifts. This has been proved by ultrastructural investigations which showed intranuclear inclusions structurally similar to virus bodies. The latter are divided into three types this allowing follow-up of the inclusions to mature forms seen in the stromal cells cytoplasm. The findings suggest primary viral affection of stromal cellular elements of aplastic anemia patients' bone marrow. The attention is also drawn to ultrastructural shifts recorded in adipose cells in aplastic anemia.
What this study does not prove
- • This study does not prove SVF is an approved treatment or a replacement for standard care.
Evidence level
Early human evidence such as case series or small samples is exploring possible benefits.
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