Level C· Early human research exploring benefitsCase Report / SeriesEurope PMCOpen access

A Novel Application of a Single-Entry Injection Technique for Non-surgical Penile Enlargement: A Case Report

Chaudhry M., Chaudhry AR.

Case Report / Series, published in Cureus (2025) — summary generated from the PubMed abstract.

Open my reading list
Level C· Early human research exploring benefitsEvidence level of this study

Early human evidence such as case series or small samples is exploring possible benefits.

  • Level A · Stronger Clinical Evidence
  • Level B · Emerging clinical evidence with positive signals
  • Level C · Early human research exploring benefits
  • Level D · Scientific groundwork from lab and animal studies
  • Emerging · Emerging topic under active research
Read the A–D evidence level guide

This page is generated from the PubMed record. The Thai description is an automated summary of bibliographic fields and the abstract, not a full translation, and is not medical advice.

Study type
Case Report / Series
Journal
Cureus (2025)
Reported sample size
—
Source database
Europe PMC
PMID
40486481
PMCID
PMC12142451
DOI
10.7759/cureus.83637

Abstract (original English)

Non-surgical penile enhancement using dermal fillers is a growing trend, yet traditional techniques often result in uneven volume distribution, poor integration, increased risk of filler migration and/or vascular complications. These limitations reduce aesthetic quality and patient satisfaction. We introduce the Cylindrical Dartos-Buck Smooth (CDS) technique, a novel single-entry, cannula-based method designed for even filler distribution within the sub-Dartos/Buck's fascial plane to achieve natural, uniform penile augmentation. We present the case of a 29-year-old male who underwent the CDS technique with 15 mL of dermal filler via an 18-G blunt-tip cannula through a single mid-shaft entry point. Dermal filler was deposited in structured micro-droplets along the target fascial layer. At six-month follow-up, the patient demonstrated a 0.63-inch increase in girth, natural tactile feel, uniform volume distribution and no complications. The patient and the injecting doctor completed a modified (adapted for penile enhancement) Global Aesthetic Improvement Scale (GAIS) to assess the results. The clinical GAIS score at six months was 2, and the patient GAIS score was 1, indicating an excellent clinical outcome and strong patient satisfaction. The CDS technique provides enhanced control, superior contouring and improved safety compared to traditional penile filler approaches. Further

What this study does not prove

  • • This study does not prove SVF is an approved treatment or a replacement for standard care.
  • • Without an adequate control group, treatment effects cannot be separated from other factors.

Evidence level

Early human evidence such as case series or small samples is exploring possible benefits.

How we grade evidence

Browse all related research

Filter the research library by this study's title keywords, author, or publication year.