Objective Assessment of Combined Orbital Fat Repositioning and Fat Grafting in Upper Eyelid Hollowing
Dien LH., Anh HT., Lam VN., Duc VV., Nguyen TH., Anh DNV.
Prospective Study on Face & Skin, published in Med Arch (2026) — summary generated from the PubMed abstract.
Early human evidence such as case series or small samples is exploring possible benefits.
- Level A · Stronger Clinical Evidence
- Level B · Emerging clinical evidence with positive signals
- Level C · Early human research exploring benefits
- Level D · Scientific groundwork from lab and animal studies
- Emerging · Emerging topic under active research
This page is generated from the PubMed record. The Thai description is an automated summary of bibliographic fields and the abstract, not a full translation, and is not medical advice.
- Study type
- Prospective Study
- Journal
- Med Arch (2026)
- Reported sample size
- —
- Source database
- Europe PMC
- PMID
- 41939494
- PMCID
- PMC13049471
- DOI
- 10.5455/medarh.2026.80.57-62
Abstract (original English)
Background Upper eyelid hollowing is a common manifestation of periorbital aging caused by soft-tissue atrophy and loss of orbital fat volume. Although various corrective techniques have been described, outcome assessment remains largely subjective. High-resolution ultrasonography may provide an objective and quantitative method for evaluating postoperative soft-tissue changes. Objective The present study aimed to evaluate the effectiveness and stability of combined orbital fat repositioning and microfragmented autologous fat grafting for the correction of moderate upper eyelid hollowing, using high-resolution ultrasonography as an objective assessment tool. Methods A prospective study was conducted in 35 female patients (70 upper eyelids), aged 40-65 years, with moderate upper eyelid hollowing (Park grade II). All patients underwent combined orbital fat pad repositioning with supplemental microfragmented autologous fat grafting. High-resolution ultrasonography was performed preoperatively and at 1, 3, and 6 months postoperatively to measure the space anterior to the upper eyelid skin (D1) and upper eyelid thickness (D2). Clinical outcomes and patient satisfaction were also evaluated. Results he mean preoperative hollowing depth was 5.88 ± 0.85 mm, and the mean grafted fat volume was 1.09 ± 0.29 mL. Postoperative ultrasonography demonstrated a significant decrease in D1 and a s
What this study does not prove
- • This study does not prove SVF is an approved treatment or a replacement for standard care.
Evidence level
Early human evidence such as case series or small samples is exploring possible benefits.
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