Level D· Scientific groundwork from lab and animal studiesAnimal StudyPubMed

The oblique rat groin flap.

Nishikawa H., Manek S., Green CJ.

Animal Study, published in Br J Plast Surg (1991) — summary generated from the PubMed abstract.

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Level D· Scientific groundwork from lab and animal studiesEvidence level of this study

Evidence from laboratory and animal studies provides groundwork for understanding mechanisms and potential before human studies continue.

  • Level A · Stronger Clinical Evidence
  • Level B · Emerging clinical evidence with positive signals
  • Level C · Early human research exploring benefits
  • Level D · Scientific groundwork from lab and animal studies
  • Emerging · Emerging topic under active research
Read the A–D evidence level guide

This page is generated from the PubMed record. The Thai description is an automated summary of bibliographic fields and the abstract, not a full translation, and is not medical advice.

Study type
Animal Study
Journal
Br J Plast Surg (1991)
Country
England
Reported sample size
—
Source database
PubMed
PMID
1711909
DOI
10.1016/0007-1226(91)90075-u

Abstract (original English)

Neovascularisation from the bed can result in the partial survival of failing rat groin flaps. This can interfere with the interpretation of pharmacological augmentation and ischaemia experiments. We describe the development of a modified rat groin flap which utilises the inguinal fat pad to diminish the effects of the bed on the skin component of the flap. The behaviour of this model is compared to that of standard rat groin flaps and flaps which have had polythene sheeting placed under them.

What this study does not prove

  • • This study does not prove SVF is an approved treatment or a replacement for standard care.
  • • This is preclinical work; animal or laboratory results cannot be applied to humans.

Evidence level

Evidence from laboratory and animal studies provides groundwork for understanding mechanisms and potential before human studies continue.

How we grade evidence
Adipose TissueAnimalsGranulation TissueGroinNeovascularization, PathologicRatsRats, Inbred StrainsSkinSkin TransplantationSurgical Flaps

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