Ortho-Biologics for Osteoarthritis.

Several human studies show positive signals, while research methods and sample sizes continue to develop.

• Level A · Stronger Clinical Evidence
• Level B · Emerging clinical evidence with positive signals
• Level C · Early human research exploring benefits
• Level D · Scientific groundwork from lab and animal studies
• Emerging · Emerging topic under active research

Abstract (original English)

Osteoarthritis (OA) is a debilitation condition that affects millions of North Americans. Aside from weight loss, activity modification, and joint replacement, little else has been effective in delaying the progression of OA or treating the symptoms of OA. Ortho-biologics have become a popular treatment option in a variety of musculoskeletal conditions, including OA. In this article, the authors explore the use of 4 key ortho-biologics in the treatment of OA, all of which have shown promising results in the literature, despite the lack of large randomized controlled trials.

Evidence level

Several human studies show positive signals, while research methods and sample sizes continue to develop.

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