Personalized Adipofascial Flap: A Game-Changer for Post-Traumatic Ulnar Nerve Neuropathy at the Wrist and Elbow
Greco A., Bizzarri M., Marcovici LL., Pagnotta A.
Retrospective Study with a reported sample of 13 on Arm & Elbow, published in J Pers Med (2025) — summary generated from the PubMed abstract.
Early human evidence such as case series or small samples is exploring possible benefits.
- Level A · Stronger Clinical Evidence
- Level B · Emerging clinical evidence with positive signals
- Level C · Early human research exploring benefits
- Level D · Scientific groundwork from lab and animal studies
- Emerging · Emerging topic under active research
This page is generated from the PubMed record. The Thai description is an automated summary of bibliographic fields and the abstract, not a full translation, and is not medical advice.
- Study type
- Retrospective Study
- Journal
- J Pers Med (2025)
- Reported sample size
- 13
- Source database
- Europe PMC
- PMID
- 41295227
- PMCID
- PMC12653049
- DOI
- 10.3390/jpm15110521
Abstract (original English)
Introduction: Post-traumatic and post-surgical ulnar nerve neuropathies at the elbow and wrist remain challenging conditions often associated with significant sensory and motor impairment. Traditional approaches such as neurolysis alone may be insufficient, especially in complex or recurrent cases. Adipofascial flaps have shown promising outcomes in peripheral nerve surgery. The aim of this study was to evaluate the outcomes of 13 patients with severe ulnar neuropathies who were treated with a size- and shape-personalized adipofascial flap for nerve coverage. Materials and Methods : We retrospectively analyzed 13 patients treated between May 2020 and May 2024 for severe post-traumatic or post-surgical ulnar neuropathies. All underwent surgical decompression, external neurolysis, and adipofascial flap coverage. Pre- and postoperative outcomes were assessed with clinical and neurological evaluations and using the QuickDASH and NRS pain scores. Discussion : All patients showed improvement in pain and sensory-motor function, including those with complications, supporting the role of flap coverage in neuroprotection. This is the first study to describe the use of adipofascial flaps for pseudo-palsy and painful neuroma-in-continuity of the ulnar nerve at the elbow and wrist level. Conclusions : Adipofascial flaps represent a safe, technically feasible, and effective option in complex
What this study does not prove
- • This study does not prove SVF is an approved treatment or a replacement for standard care.
- • Without an adequate control group, treatment effects cannot be separated from other factors.
Evidence level
Early human evidence such as case series or small samples is exploring possible benefits.
How we grade evidenceBrowse all related research
Filter the research library by this study's title keywords, author, or publication year.
Related research
- Level AMeta-analysisEurope PMC
Comparison of nonsurgical treatment approaches for partial rotator cuff tears: a systematic review and meta-analysis
Meta-analysis with a reported sample of 137 on Rotator Cuff, Shoulder Pain, published in JSES Rev Rep Tech (2026) — summary generated from the PubMed abstract.
- 2026
- n = 137
JSES Rev Rep Tech - Level AMeta-analysisPubMed
Hyaluronate Acid Plus Platelet-Rich Plasma Is Superior to Steroids for Pain Relief Less Than 6 Months Using Injection Therapy of Partial Rotator Cuff Tears: A Systematic Review and Network Meta-analysis.
Meta-analysis on Rotator Cuff, published in Arthroscopy (2024) — summary generated from the PubMed abstract.
- 2024
Arthroscopy6 citations - Level ASystematic ReviewEurope PMC
Challenges and opportunities in vascularized composite allotransplantation of joints: a systematic literature review
Systematic Review with a reported sample of 14 on Knee, Arm & Elbow, published in Front Immunol (2023) — summary generated from the PubMed abstract.
- 2023
- n = 14
Front Immunol3 citations - Level ASystematic ReviewEurope PMC
Interventions for treating proximal humeral fractures in adults
Systematic Review with a reported sample of 3179 on Face & Skin, Shoulder, Arm & Elbow, published in Cochrane Database Syst Rev (2022) — summary generated from the PubMed abstract.
- 2022
- n = 3179
Cochrane Database Syst Rev84 citations - Level ASystematic ReviewPubMed
Cell therapy efficacy and safety in treating tendon disorders: a systemic review of clinical studies.
Systematic Review with a reported sample of 658 on Tendon Injury, Rotator Cuff, published in J Exp Orthop (2022) — summary generated from the PubMed abstract.
- 2022
- n = 658
J Exp Orthop16 citations - Level AMeta-analysisEurope PMC
Mesenchymal Stem Cells Use in the Treatment of Tendon Disorders: A Systematic Review and Meta-Analysis of Prospective Clinical Studies
Meta-analysis on Tendon Injury, Rotator Cuff, published in Ann Rehabil Med (2021) — summary generated from the PubMed abstract.
- 2021
Ann Rehabil Med17 citations