Level C· Early human research exploring benefitsRetrospective StudyEurope PMCOpen access

Photographic Comparison of Malar Projection in 100 Facelift Patients Treated with and without Fat Injection

Swanson E.

Retrospective Study with a reported sample of 61 on Face & Skin, published in Plast Reconstr Surg Glob Open (2020) — summary generated from the PubMed abstract.

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Level C· Early human research exploring benefitsEvidence level of this study

Early human evidence such as case series or small samples is exploring possible benefits.

  • Level A · Stronger Clinical Evidence
  • Level B · Emerging clinical evidence with positive signals
  • Level C · Early human research exploring benefits
  • Level D · Scientific groundwork from lab and animal studies
  • Emerging · Emerging topic under active research
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This page is generated from the PubMed record. The Thai description is an automated summary of bibliographic fields and the abstract, not a full translation, and is not medical advice.

Study type
Retrospective Study
Journal
Plast Reconstr Surg Glob Open (2020)
Reported sample size
61
Source database
Europe PMC
PMID
33173678
PMCID
PMC7647636
DOI
10.1097/gox.0000000000003162
Citations
2

Abstract (original English)

Background Facelifts are frequently combined with fat injection to restore volume. However, the efficacy of simultaneous fat grafting has not been objectively evaluated in a large number of patients that includes a control group. This study was undertaken to fill this gap in our knowledge base. Methods A retrospective comparative cohort study was undertaken among 100 patients who underwent a subsuperficial musculoaponeurotic system facelift with (n = 61) or without (n = 39) simultaneous malar fat injection. Rigorously standardized photographs were obtained 1, 3, and 6 months after surgery, including oblique photographs with the nasion aligned with the far inner canthus. Malar projection and area were measured with the assistance of a computer imaging software. Results Fat injection produced a significant ( P P P ≤ 0.001). The increase was sustained at follow-up times up to 6 months, and 1 year in a smaller patient cohort (n = 44), with no evidence of a decline or rebound. The calculated fat retention was 34%. Conclusions Fat injection at the time of a facelift effectively adds malar volume, and this increase is sustained at time points up to 1 year after surgery, consistent with the cell survival theory.

What this study does not prove

  • • This study does not prove SVF is an approved treatment or a replacement for standard care.
  • • Without an adequate control group, treatment effects cannot be separated from other factors.

Evidence level

Early human evidence such as case series or small samples is exploring possible benefits.

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