Pleomorphic adenoma of the lip: a case report and literature review
Ali RM., Ali RM., Qaradakhy AJ., Hiwa DS., Abdullah AM., Omar DA.
Case Report / Series, published in J Surg Case Rep (2025) — summary generated from the PubMed abstract.
Early human evidence such as case series or small samples is exploring possible benefits.
- Level A · Stronger Clinical Evidence
- Level B · Emerging clinical evidence with positive signals
- Level C · Early human research exploring benefits
- Level D · Scientific groundwork from lab and animal studies
- Emerging · Emerging topic under active research
This page is generated from the PubMed record. The Thai description is an automated summary of bibliographic fields and the abstract, not a full translation, and is not medical advice.
- Study type
- Case Report / Series
- Journal
- J Surg Case Rep (2025)
- Reported sample size
- —
- Source database
- Europe PMC
- PMID
- 40376544
- PMCID
- PMC12078932
- DOI
- 10.1093/jscr/rjaf311
Abstract (original English)
Pleomorphic adenoma (PA) most commonly affects the major salivary glands but can also involve the minor salivary glands, particularly those of the hard and soft palate. However, the current study aims to present a case of upper lip PA. A 29-year-old male presented with a painless, firm, slow-growing swelling (1.5 × 1.5 cm) on the left upper lip. Ultrasonography showed a solid, hypoechoic nodule with irregular margins and mild peripheral vascularity. The encapsulated tumor was excised, and histopathology confirmed PA. At the 7-month follow-up, no evidence of recurrence was observed. Though typically seen in adults aged 40-70, PA can affect younger patients. Complete excision with clear margins is essential due to the risk of recurrence or malignant transformation. PA should be considered in the differential diagnosis of upper lip swellings.
What this study does not prove
- • This study does not prove SVF is an approved treatment or a replacement for standard care.
- • Without an adequate control group, treatment effects cannot be separated from other factors.
Evidence level
Early human evidence such as case series or small samples is exploring possible benefits.
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