SVF
Level D· Scientific groundwork from lab and animal studiesLaboratory StudyPubMed

Preparation of Decellularized Amniotic Membrane and Adipose-Derived Stromal/Stem Cell Seeding.

Tauseef H., Ahmed K., Salim A., Mohiuddin OA.

Laboratory Study on Scar, published in Methods Mol Biol (2024) — summary generated from the PubMed abstract.

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Level D· Scientific groundwork from lab and animal studiesEvidence level of this study

Evidence from laboratory and animal studies provides groundwork for understanding mechanisms and potential before human studies continue.

  • Level A · Stronger Clinical Evidence
  • Level B · Emerging clinical evidence with positive signals
  • Level C · Early human research exploring benefits
  • Level D · Scientific groundwork from lab and animal studies
  • Emerging · Emerging topic under active research
Read the A–D evidence level guide

This page is generated from the PubMed record. The Thai description is an automated summary of bibliographic fields and the abstract, not a full translation, and is not medical advice.

Study type
Laboratory Study
Journal
Methods Mol Biol (2024)
Country
United States
Reported sample size
—
Source database
PubMed
PMID
38478235
DOI
10.1007/978-1-0716-3762-3_14
Citations
2

Abstract (original English)

Amniotic membrane, being part of the placenta, is discarded as medical waste after childbirth. It can be decellularized to convert it into an acellular material while retaining the extracellular matrix. Such amniotic membrane grafts support stem cell adhesion, growth, and proliferation. These properties make it a useful candidate to be used as a bio-scaffold in regenerative medicine. This chapter describes a method for the decellularization of the amniotic membrane. Furthermore, the method for seeding adipose-derived stem cells on the decellularized amniotic membrane is described.

What this study does not prove

  • • This study does not prove SVF is an approved treatment or a replacement for standard care.
  • • This is preclinical work; animal or laboratory results cannot be applied to humans.

Evidence level

Evidence from laboratory and animal studies provides groundwork for understanding mechanisms and potential before human studies continue.

How we grade evidence
Tissue ScaffoldsAmnionAdipocytesExtracellular MatrixStem CellsTissue Engineering
Scar
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