Level C· Early human research exploring benefitsCase Report / SeriesEurope PMCOpen access

Prosthetic nipple areola complex reconstruction after breast reduction: a case report

Taglialatela Scafati S., Schonauer F., d'Angelo D., D'Andrea F., Cavaliere A.

Case Report / Series, published in Case Reports Plast Surg Hand Surg (2026) — summary generated from the PubMed abstract.

Open my reading list
Level C· Early human research exploring benefitsEvidence level of this study

Early human evidence such as case series or small samples is exploring possible benefits.

  • Level A · Stronger Clinical Evidence
  • Level B · Emerging clinical evidence with positive signals
  • Level C · Early human research exploring benefits
  • Level D · Scientific groundwork from lab and animal studies
  • Emerging · Emerging topic under active research
Read the A–D evidence level guide

This page is generated from the PubMed record. The Thai description is an automated summary of bibliographic fields and the abstract, not a full translation, and is not medical advice.

Study type
Case Report / Series
Journal
Case Reports Plast Surg Hand Surg (2026)
Reported sample size
—
Source database
Europe PMC
PMID
41938120
PMCID
PMC13045190
DOI
10.1080/23320885.2026.2648923

Abstract (original English)

Total nipple-areola necrosis following breast reduction is a rare and unfortunate event. Several causes may be responsible for it, including compression of the vascular pedicle, venous congestion, infection, hematoma, or inappropriate surgical technique. Considering the importance of the nipple areola complex (NAC) in the overall appearance of a breast mound, it is clear that the complete loss of the nipple areola complex is one of the most traumatizing complications for both the patient and the surgeon. Herein we describe the case of a patient who developed complete NAC necrosis following breast reduction. After initial wound management and stabilization, the patient underwent delayed reconstruction using an innovative NAC implant specifically designed to restore nipple projection and contour. Delayed reconstruction of the left NAC was performed using a silicone implant (FixNip, GC Aesthetics, Caesarea, Israel), specifically designed to restore natural projection and contour. The implant was positioned under local anesthesia as an outpatient procedure. Postoperative course was uneventful. At 8 months, after ultrasound confirmed proper implant integration, medical tattooing of the areola was completed. Implant based NAC reconstruction achieved a stable and well-projected NAC reconstruction. No minor or major complications occurred, and the patient reported high satisfaction wit

What this study does not prove

  • • This study does not prove SVF is an approved treatment or a replacement for standard care.
  • • Without an adequate control group, treatment effects cannot be separated from other factors.

Evidence level

Early human evidence such as case series or small samples is exploring possible benefits.

How we grade evidence

Browse all related research

Filter the research library by this study's title keywords, author, or publication year.