Level D· Scientific groundwork from lab and animal studiesAnimal StudyPubMed

Protein-engineered injectable hydrogel to improve retention of transplanted adipose-derived stem cells.

Parisi-Amon A., Mulyasasmita W., Chung C., Heilshorn SC.

Animal Study, published in Adv Healthc Mater (2012) — summary generated from the PubMed abstract.

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Level D· Scientific groundwork from lab and animal studiesEvidence level of this study

Evidence from laboratory and animal studies provides groundwork for understanding mechanisms and potential before human studies continue.

  • Level A · Stronger Clinical Evidence
  • Level B · Emerging clinical evidence with positive signals
  • Level C · Early human research exploring benefits
  • Level D · Scientific groundwork from lab and animal studies
  • Emerging · Emerging topic under active research
Read the A–D evidence level guide

This page is generated from the PubMed record. The Thai description is an automated summary of bibliographic fields and the abstract, not a full translation, and is not medical advice.

Study type
Animal Study
Journal
Adv Healthc Mater (2012)
Country
Germany
Reported sample size
—
Source database
PubMed
PMID
23184882
PMCID
PMC3926432
DOI
10.1002/adhm.201200293
Citations
101

Abstract (original English)

Improved retention of transplanted stem cells is achieved through minimally invasive delivery in MITCH, a mixing-induced two-component hydrogel that was engineered to possess shear-thinning and self-healing thixotropic properties. MITCH, an ideal injectable cell-delivery vehicle, supports 3D stem-cell culture, resulting in high cell viability and physiologically relevant cell morphology.

What this study does not prove

  • • This study does not prove SVF is an approved treatment or a replacement for standard care.
  • • This is preclinical work; animal or laboratory results cannot be applied to humans.

Evidence level

Evidence from laboratory and animal studies provides groundwork for understanding mechanisms and potential before human studies continue.

How we grade evidence
Adipose TissueAnimalsBiopolymersHydrogel, Polyethylene Glycol DimethacrylateInjectionsMaleMaterials TestingMiceMice, NudeMice, Transgenic

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