Level D· Scientific groundwork from lab and animal studiesNarrative ReviewEurope PMCOpen access

Radiation-induced skin injury: pathogenesis, treatment, and management

Yang X., Ren H., Guo X., Hu C., Fu J.

Narrative Review, published in Aging (Albany NY) (2020) — summary generated from the PubMed abstract.

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Level D· Scientific groundwork from lab and animal studiesEvidence level of this study

Evidence from laboratory and animal studies provides groundwork for understanding mechanisms and potential before human studies continue.

  • Level A · Stronger Clinical Evidence
  • Level B · Emerging clinical evidence with positive signals
  • Level C · Early human research exploring benefits
  • Level D · Scientific groundwork from lab and animal studies
  • Emerging · Emerging topic under active research
Read the A–D evidence level guide

This page is generated from the PubMed record. The Thai description is an automated summary of bibliographic fields and the abstract, not a full translation, and is not medical advice.

Study type
Narrative Review
Journal
Aging (Albany NY) (2020)
Reported sample size
—
Source database
Europe PMC
PMID
33202382
PMCID
PMC7746368
DOI
10.18632/aging.103932
Citations
135

Abstract (original English)

Radiation-induced skin injury (RSI) refers to a frequently occurring complication of radiation therapy. Nearly 90% of patients having received radiation therapy underwent moderate-to-severe skin reactions, severely reducing patients' quality of life and adversely affecting their disease treatment. No gold standard has been formulated for RSIs. In the present study, the mechanism of RSI and topical medications was discussed. Besides, this study can be referenced for clinicians to treat RSIs to guide subsequent clinical medicine.

What this study does not prove

  • • This study does not prove SVF is an approved treatment or a replacement for standard care.
  • • This is a narrative review: it collects no new patient data and does not systematically appraise evidence quality.

Evidence level

Evidence from laboratory and animal studies provides groundwork for understanding mechanisms and potential before human studies continue.

How we grade evidence
SkinAnimalsHumansRadiodermatitisFibrosisDermatologic AgentsTreatment OutcomeRadiotherapyAdministration, CutaneousSeverity of Illness Index

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