Level D· Scientific groundwork from lab and animal studiesAnimal StudyPubMed

Ready, set, but no go: Skin fat comes preloaded with waiting precursors.

Shin JW., Plikus MV.

Animal Study, published in Cell Stem Cell (2025) — summary generated from the PubMed abstract.

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Level D· Scientific groundwork from lab and animal studiesEvidence level of this study

Evidence from laboratory and animal studies provides groundwork for understanding mechanisms and potential before human studies continue.

  • Level A · Stronger Clinical Evidence
  • Level B · Emerging clinical evidence with positive signals
  • Level C · Early human research exploring benefits
  • Level D · Scientific groundwork from lab and animal studies
  • Emerging · Emerging topic under active research
Read the A–D evidence level guide

This page is generated from the PubMed record. The Thai description is an automated summary of bibliographic fields and the abstract, not a full translation, and is not medical advice.

Study type
Animal Study
Journal
Cell Stem Cell (2025)
Country
United States
Reported sample size
—
Source database
PubMed
PMID
40912233
DOI
10.1016/j.stem.2025.08.003

Abstract (original English)

Fat depots across the body dynamically tune their sizes in response to nutrient demands and nonmetabolic cues. Writing in Cell Stem Cell, Rivera-Gonzalez et al. 1 report that skin fat, notable for its ability to rapidly expand, harbors molecularly distinct precursors, primed for proliferation and differentiation into mature adipocytes.

What this study does not prove

  • • This study does not prove SVF is an approved treatment or a replacement for standard care.
  • • This is preclinical work; animal or laboratory results cannot be applied to humans.

Evidence level

Evidence from laboratory and animal studies provides groundwork for understanding mechanisms and potential before human studies continue.

How we grade evidence
SkinHumansAnimalsAdipocytesCell DifferentiationStem CellsAdipose TissueCell Proliferation

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