Level C· Early human research exploring benefitsRetrospective StudyEurope PMCOpen access

Real- vs High-Definition Ultrasound-Assisted Liposuction in Men: Long-Term Outcomes and the Role of Helium Plasma Skin Tightening

Celik N., Akgun Demir I., Kurt S., Keskin I.

Retrospective Study, published in Aesthet Surg J Open Forum (2025) — summary generated from the PubMed abstract.

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Level C· Early human research exploring benefitsEvidence level of this study

Early human evidence such as case series or small samples is exploring possible benefits.

  • Level A · Stronger Clinical Evidence
  • Level B · Emerging clinical evidence with positive signals
  • Level C · Early human research exploring benefits
  • Level D · Scientific groundwork from lab and animal studies
  • Emerging · Emerging topic under active research
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This page is generated from the PubMed record. The Thai description is an automated summary of bibliographic fields and the abstract, not a full translation, and is not medical advice.

Study type
Retrospective Study
Journal
Aesthet Surg J Open Forum (2025)
Reported sample size
—
Source database
Europe PMC
PMID
41394264
PMCID
PMC12697575
DOI
10.1093/asjof/ojaf157

Abstract (original English)

Background Male body contouring has evolved from conventional debulking to high-definition liposuction (HDL) etching and, more recently, a "real-definition" c (RDL) approach emphasizing natural contours. The role of helium-plasma skin tightening (HPST) as an adjunct remains uncertain. Objectives To compare long-term patient-reported outcomes, complications, and revision rates between RDL and HDL in men undergoing ultrasound-assisted liposuction (UAL), and to evaluate the selective role of HPST in improving skin quality. Methods A retrospective analysis was performed on 743 male patients who underwent primary UAL between 2008 and 2024. Patients were grouped by era: conventional (2008-2011), HDL (2011-2014), RDL (2015-2019), and RDL with HPST (2019-2024). Outcomes included BODY-Q satisfaction, complication severity, and revision rates. Regression, mediation, and propensity-score matching analyses were applied to identify predictors of durable satisfaction and recommendation. Results Mean satisfaction improved across eras: 59.3 (2008-2011), 57.7 (2011-2014), 66.8 (2015-2019), and 73.8 (2019-2024). HDL patients showed the lowest durable scores despite high early ratings and were most associated with self-reported "fake abs," which correlated with reduced BODY-Q domains. RDL produced more stable outcomes, particularly in men with BMI ≤25 and ≥4 exercise sessions/week. Sports frequen

What this study does not prove

  • • This study does not prove SVF is an approved treatment or a replacement for standard care.
  • • Without an adequate control group, treatment effects cannot be separated from other factors.

Evidence level

Early human evidence such as case series or small samples is exploring possible benefits.

How we grade evidence

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