Level B· Emerging clinical evidence with positive signalsClinical TrialEurope PMCOpen access

Recent trends in stem cell therapy for premature ovarian insufficiency and its therapeutic potential: a review

Na J., Kim GJ.

Clinical Trial, published in J Ovarian Res (2020) — summary generated from the PubMed abstract.

Open my reading list
Level B· Emerging clinical evidence with positive signalsEvidence level of this study

Several human studies show positive signals, while research methods and sample sizes continue to develop.

  • Level A · Stronger Clinical Evidence
  • Level B · Emerging clinical evidence with positive signals
  • Level C · Early human research exploring benefits
  • Level D · Scientific groundwork from lab and animal studies
  • Emerging · Emerging topic under active research
Read the A–D evidence level guide

This page is generated from the PubMed record. The Thai description is an automated summary of bibliographic fields and the abstract, not a full translation, and is not medical advice.

Study type
Clinical Trial
Journal
J Ovarian Res (2020)
Reported sample size
—
Source database
Europe PMC
PMID
32576209
PMCID
PMC7313218
DOI
10.1186/s13048-020-00671-2
Citations
44

Abstract (original English)

Stem cell therapy is attracting attention in the field of regenerative medicine and is advancing rapidly. Many recent studies have applied stem cell therapy to treat reproductive system diseases; however, data are not yet available as to whether this therapy shows enhanced therapeutic effects. This paper analyzes recent preclinical studies on stem cell therapy for ovarian dysfunction in several types of animal models. Several clinical trials and pending projects are also discussed. This review will provide a background for developing stem cell therapies to enhance ovarian function.

What this study does not prove

  • • This study does not prove SVF is an approved treatment or a replacement for standard care.

Evidence level

Several human studies show positive signals, while research methods and sample sizes continue to develop.

How we grade evidence
Mesenchymal Stem CellsAnimalsHumansMiceRatsDisease Models, AnimalStem Cell TransplantationAdultFemalePrimary Ovarian Insufficiency

Browse all related research

Filter the research library by this study's title keywords, author, or publication year.