Level D· Scientific groundwork from lab and animal studiesLaboratory StudyEurope PMCOpen access

Refractory Alopecia Areata of the Beard: Novel Improvement Through Exosome Therapy With Signs of Hair Repigmentation

Shadid A., Nagshabandi KN., AlRuhaimi DK., Al-Omair A., Alsadhan A.

Laboratory Study on Scar, Hair Loss, published in Clin Case Rep (2025) — summary generated from the PubMed abstract.

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Level D· Scientific groundwork from lab and animal studiesEvidence level of this study

Evidence from laboratory and animal studies provides groundwork for understanding mechanisms and potential before human studies continue.

  • Level A · Stronger Clinical Evidence
  • Level B · Emerging clinical evidence with positive signals
  • Level C · Early human research exploring benefits
  • Level D · Scientific groundwork from lab and animal studies
  • Emerging · Emerging topic under active research
Read the A–D evidence level guide

This page is generated from the PubMed record. The Thai description is an automated summary of bibliographic fields and the abstract, not a full translation, and is not medical advice.

Study type
Laboratory Study
Journal
Clin Case Rep (2025)
Reported sample size
—
Source database
Europe PMC
PMID
41356640
PMCID
PMC12679482
DOI
10.1002/ccr3.71558

Abstract (original English)

Exosome injections derived from human umbilical cord, with or without polydeoxyribonucleotide, induced robust regrowth, repigmentation of previously white beard hairs, and scar improvement in a 35-year-old man with refractory alopecia areata of the beard, suggesting a promising minimally invasive regenerative option.

What this study does not prove

  • • This study does not prove SVF is an approved treatment or a replacement for standard care.
  • • This is preclinical work; animal or laboratory results cannot be applied to humans.

Evidence level

Evidence from laboratory and animal studies provides groundwork for understanding mechanisms and potential before human studies continue.

How we grade evidence

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