SVF
Level B· Emerging Clinical EvidenceRandomized Controlled Trial

Regeneration of full thickness common extensor tendon tear after percutaneous microfragmented adipose graft.

Siddiqui IJ., Ritner A., Mahadevan S., Dineen KJ., Desronvilles R.

Randomized Controlled Trial on Tendon Injury, Chronic Inflammation, published in Regen Med (2024) — summary generated from the PubMed abstract.

This page is generated from the PubMed record. The Thai description is an automated summary of bibliographic fields and the abstract, not a full translation, and is not medical advice.

Study type
Randomized Controlled Trial
Journal
Regen Med (2024)
Country
England
Reported sample size
—
PMID
39387455
DOI
10.1080/17460751.2024.2393555

Abstract (original English)

Tennis elbow, also commonly known as lateral epicondylitis or common extensor tendinosis, is a common musculoskeletal injury in the adult population. Currently, the standard treatment regimen prescribed for this injury involves a combination of rest, physical therapy, bracing and anti-inflammatory medications. If refractory to these conservative measures, platelet-rich plasma has been shown effective. However, in the case of full thickness tears, surgery has remained the only treatment option until now. We present a case report of a 56-year-old man with a diagnosis of a left large full thickness tear and rupture with retraction of his common extensor tendon (CET) following a corticosteroid injection. The patient was treated with microfragmented adipose transfer. He was re-evaluated around 7 weeks and again at 15 weeks post-treatment and demonstrated ultrasound evidence of complete bridging and remodeling of his prior full thickness CET tear and resolution of retraction. This case presents a promising option for patients with full thickness CET tears who would like to refrain from or are unable to have surgery. Further research and possible randomized controlled trials are needed to further assess the full efficacy of microfragmented adipose transfer in the treatment of full thickness CET tears. Adipose cells from a patient’s own body fat are one of the best sources of mesenchym

What this study does not prove

  • • This study does not prove SVF is an approved treatment or a replacement for standard care.

Evidence level

Several human studies exist, but sample sizes, methodology, or follow-up remain limited, so conclusions are not firm.

How we grade evidence
HumansMaleMiddle AgedAdipose TissueTendon InjuriesRegenerationTennis Elbow
Arm & ElbowTendon InjuryChronic Inflammation
View on PubMedDOI

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