Level D· Scientific groundwork from lab and animal studiesNarrative ReviewEurope PMCOpen access

[Regeneration - A New Therapeutic Dimension in Otorhinolaryngology]

Rotter N., Zenobi-Wong M.

Narrative Review, published in Laryngorhinootologie (2018) — summary generated from the PubMed abstract.

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Level D· Scientific groundwork from lab and animal studiesEvidence level of this study

Evidence from laboratory and animal studies provides groundwork for understanding mechanisms and potential before human studies continue.

  • Level A · Stronger Clinical Evidence
  • Level B · Emerging clinical evidence with positive signals
  • Level C · Early human research exploring benefits
  • Level D · Scientific groundwork from lab and animal studies
  • Emerging · Emerging topic under active research
Read the A–D evidence level guide

This page is generated from the PubMed record. The Thai description is an automated summary of bibliographic fields and the abstract, not a full translation, and is not medical advice.

Study type
Narrative Review
Journal
Laryngorhinootologie (2018)
Reported sample size
—
Source database
Europe PMC
PMID
29905357
PMCID
PMC6290928
DOI
10.1055/s-0043-122309

Abstract (original English)

Regeneration as a therapeutic priniciple and regenerative medicine in general are promising new strategies to add new therapeutic dimensions to our current treatment options. Today, reconstructive surgery, drugs and implants such as the cochlear implant can replace the functions of damaged tissues. In contrast, regenerative therapies aim at the replacement of the damaged tissues themselves while at the same time replacing their lost tissue function. In this review article new technologies such as 3D-bioprinting and the application of decellularised tissues as biomaterials are introduced and explained. A summary of current preclinical and clinical regenerative studies in otorhinolaryngology is complementing these basic aspects.

What this study does not prove

  • • This study does not prove SVF is an approved treatment or a replacement for standard care.
  • • This is a narrative review: it collects no new patient data and does not systematically appraise evidence quality.

Evidence level

Evidence from laboratory and animal studies provides groundwork for understanding mechanisms and potential before human studies continue.

How we grade evidence
HumansOtorhinolaryngologic DiseasesOtorhinolaryngologic Surgical ProceduresTissue EngineeringRegenerative MedicineBioprintingPrinting, Three-DimensionalPlastic Surgery Procedures

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