Level D· Scientific groundwork from lab and animal studiesLaboratory StudyPubMedOpen access

Regenerative Approach With Autologous Fat Grafting and Stem Cells for the Treatment of Post-Traumatic Anal Incontinence: A Case Report.

da Silva Nishimura A., Silva GDA., Figueira VH., Nishimoto EI., Menardi PLN., Passaglia IRG.

Laboratory Study, published in Clin Case Rep (2026) — summary generated from the PubMed abstract.

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Level D· Scientific groundwork from lab and animal studiesEvidence level of this study

Evidence from laboratory and animal studies provides groundwork for understanding mechanisms and potential before human studies continue.

  • Level A · Stronger Clinical Evidence
  • Level B · Emerging clinical evidence with positive signals
  • Level C · Early human research exploring benefits
  • Level D · Scientific groundwork from lab and animal studies
  • Emerging · Emerging topic under active research
Read the A–D evidence level guide

This page is generated from the PubMed record. The Thai description is an automated summary of bibliographic fields and the abstract, not a full translation, and is not medical advice.

Study type
Laboratory Study
Journal
Clin Case Rep (2026)
Country
England
Reported sample size
—
Source database
PubMed
PMID
41522849
PMCID
PMC12783066
DOI
10.1002/ccr3.71619
Citations
1

Abstract (original English)

Autologous fat grafting enriched with mesenchymal stem cells is a promising minimally invasive regenerative therapy for post-traumatic anal incontinence. This approach may restore continence and quality of life, even when structural sphincter defects persist.

What this study does not prove

  • • This study does not prove SVF is an approved treatment or a replacement for standard care.
  • • This is preclinical work; animal or laboratory results cannot be applied to humans.

Evidence level

Evidence from laboratory and animal studies provides groundwork for understanding mechanisms and potential before human studies continue.

How we grade evidence

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