Level D· Scientific groundwork from lab and animal studiesNarrative ReviewEurope PMCOpen access

Reinforcing Restorative Dentistry: The Dual Role of Carbon Nanotubes in Material Enhancement and Therapy

Bapat RA., Bedia SV., Bedia AS., Kuan EKS., Parolia A., Abdulla AM.

Narrative Review on Face & Skin, published in Int J Dent (2025) — summary generated from the PubMed abstract.

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Level D· Scientific groundwork from lab and animal studiesEvidence level of this study

Evidence from laboratory and animal studies provides groundwork for understanding mechanisms and potential before human studies continue.

  • Level A · Stronger Clinical Evidence
  • Level B · Emerging clinical evidence with positive signals
  • Level C · Early human research exploring benefits
  • Level D · Scientific groundwork from lab and animal studies
  • Emerging · Emerging topic under active research
Read the A–D evidence level guide

This page is generated from the PubMed record. The Thai description is an automated summary of bibliographic fields and the abstract, not a full translation, and is not medical advice.

Study type
Narrative Review
Journal
Int J Dent (2025)
Reported sample size
—
Source database
Europe PMC
PMID
41195300
PMCID
PMC12585840
DOI
10.1155/ijod/5535891

Abstract (original English)

Carbon nanotubes (CNTs) have garnered considerable interest in dentistry due to their exceptional properties, including high tensile strength (TS), low weight, chemical stability, and antimicrobial activity. These attributes make CNTs valuable for enhancing the mechanical performance and therapeutic potential of dental materials. Recent advances have demonstrated their effectiveness in dental composites, improving flexural strength (FS), wear resistance, and minimizing polymerization shrinkage. Furthermore, their antimicrobial properties contribute to the prevention of secondary caries and increase the longevity of restorations. Beyond restorative uses, CNTs show promise in drug delivery and tissue engineering, particularly in bone regeneration and periodontal therapy. However, concerns about biocompatibility remain, primarily due to potential cytotoxicity associated with metal impurities. Surface functionalization is critical in improving biological interactions and reducing toxicity. Despite these challenges, CNT-based dental materials represent a promising frontier in strengthening restoration and combating microbial threats. This review explores the dual role of CNTs in restorative dentistry and targeted therapeutics, synthesizing current evidence and outlining future directions for clinical application.

What this study does not prove

  • • This study does not prove SVF is an approved treatment or a replacement for standard care.
  • • This is a narrative review: it collects no new patient data and does not systematically appraise evidence quality.

Evidence level

Evidence from laboratory and animal studies provides groundwork for understanding mechanisms and potential before human studies continue.

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