Level D· Scientific groundwork from lab and animal studiesLaboratory StudyPubMed

Research Trends in Stem Cell Therapy for Stress Urinary Incontinence from 2000 to 2025: A Bibliometric Analysis.

Chen J., Zhi Y., Liu W., Deng Y., Zhong Q., Zhang W.

Laboratory Study, published in Curr Stem Cell Res Ther (2026) — summary generated from the PubMed abstract.

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Level D· Scientific groundwork from lab and animal studiesEvidence level of this study

Evidence from laboratory and animal studies provides groundwork for understanding mechanisms and potential before human studies continue.

  • Level A · Stronger Clinical Evidence
  • Level B · Emerging clinical evidence with positive signals
  • Level C · Early human research exploring benefits
  • Level D · Scientific groundwork from lab and animal studies
  • Emerging · Emerging topic under active research
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This page is generated from the PubMed record. The Thai description is an automated summary of bibliographic fields and the abstract, not a full translation, and is not medical advice.

Study type
Laboratory Study
Journal
Curr Stem Cell Res Ther (2026)
Country
United Arab Emirates
Reported sample size
—
Source database
PubMed
PMID
41937542
DOI
10.2174/011574888X421407251212103110

Abstract (original English)

Stress Urinary Incontinence (SUI), the most prevalent type of urinary incontinence, has received increased attention from researchers because of its significant impact on daily life. In addition to conventional treatments, stem cell therapy is increasingly being recommended for SUI treatment. In this study, we perform a bibliometric analysis of published studies on the use of stem cell therapy for SUI treatment. To collect and quantitatively evaluate the relevant literature in the Web of Science Core Collection (WoSCC), PubMed, and Scopus databases, we retrieved studies published from 2000 to 2025 and used CiteSpace for visual analysis. Microsoft Office Excel 2019 was used to sort the data and generate tables. A total of 316 articles were retrieved on April 01, 2025, after data merging. The annual number of publications presented an increasing trend initially, but then decreased. The keywords "stress urinary incontinence", "urinary incontinence", "cell therapy", "adipose-derived stem cell", and "regenerative medicine" were the top five keywords used in the co-occurrence analysis. In terms of publication region, the USA has the largest number of publications, followed by China. Case Western Reserve University and Wake Forest University were the top 2 institutions according to the institution map. Michael B. Chancellor was the most productive author, with 14 publications. J Urolo

What this study does not prove

  • • This study does not prove SVF is an approved treatment or a replacement for standard care.
  • • This is preclinical work; animal or laboratory results cannot be applied to humans.

Evidence level

Evidence from laboratory and animal studies provides groundwork for understanding mechanisms and potential before human studies continue.

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