RETRACTION: Sex-Dependent Paracrine Effect of Conditioned Media From Adipose Tissue Derived Mesenchymal Stem Cells on Prostate Cancer Cells.
Laboratory Study, published in J Cell Mol Med (2025) — summary generated from the PubMed abstract.
Evidence from laboratory and animal studies provides groundwork for understanding mechanisms and potential before human studies continue.
- Level A · Stronger Clinical Evidence
- Level B · Emerging clinical evidence with positive signals
- Level C · Early human research exploring benefits
- Level D · Scientific groundwork from lab and animal studies
- Emerging · Emerging topic under active research
This page is generated from the PubMed record. The Thai description is an automated summary of bibliographic fields and the abstract, not a full translation, and is not medical advice.
- Study type
- Laboratory Study
- Journal
- J Cell Mol Med (2025)
- Country
- England
- Reported sample size
- —
- Source database
- PubMed
- PMID
- 41427454
- DOI
- 10.1111/jcmm.71001
Abstract (original English)
A. Mirzaei, R. Mashhadi, Z. Aghsaeifard, M. Izadi, S. N. H. Dougaheh, R. Omid, F. Guitynavard, P. Nikoofar, and S. M. K. Aghamir, "Sex-Dependent Paracrine Effect of Conditioned Media From Adipose Tissue Derived Mesenchymal Stem Cells on Prostate Cancer Cells," Journal of Cellular and Molecular Medicine 29, no. 9 (2025): e70569, https://doi.org/10.1111/jcmm.70569. The above article, published online on 12 May 2025 in Wiley Online Library (wileyonlinelibrary.com), has been retracted by agreement between; the authors; the journal Editor-in-Chief, Stefan N. Constantinescu; the Foundation for Cellular and Molecular Medicine; and John Wiley & Sons Ltd. The retraction has been agreed upon following concerns raised by a third-party regarding image duplication. The investigation confirmed an overlap between the LNCaP MCM and FCM images in Figure 2. In addition, the DU145 and LNCaP control images in Figure 3 were found to be identical. The authors fully cooperated with the investigation, explaining that the duplication was due to an inadvertent error in figure preparation. They also provided some data; however, the data provided was insufficient to restore the editor's confidence in the results and conclusions. Consequently, the editors consider the findings unreliable.
What this study does not prove
- • This study does not prove SVF is an approved treatment or a replacement for standard care.
- • This is preclinical work; animal or laboratory results cannot be applied to humans.
Evidence level
Evidence from laboratory and animal studies provides groundwork for understanding mechanisms and potential before human studies continue.
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