Level D· Scientific groundwork from lab and animal studiesLaboratory StudyEurope PMCOpen access

Rogue stem cell clinics

Murray IR., Chahla J., Frank RM., Piuzzi NS., Mandelbaum BR., Dragoo JL.

Laboratory Study, published in Bone Joint J (2020) — summary generated from the PubMed abstract.

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Level D· Scientific groundwork from lab and animal studiesEvidence level of this study

Evidence from laboratory and animal studies provides groundwork for understanding mechanisms and potential before human studies continue.

  • Level A · Stronger Clinical Evidence
  • Level B · Emerging clinical evidence with positive signals
  • Level C · Early human research exploring benefits
  • Level D · Scientific groundwork from lab and animal studies
  • Emerging · Emerging topic under active research
Read the A–D evidence level guide

This page is generated from the PubMed record. The Thai description is an automated summary of bibliographic fields and the abstract, not a full translation, and is not medical advice.

Study type
Laboratory Study
Journal
Bone Joint J (2020)
Reported sample size
—
Source database
Europe PMC
PMID
32009438
PMCID
PMC7002842
DOI
10.1302/0301-620x.102b2.bjj-2019-1104.r1
Citations
29

Abstract (original English)

Cell therapies hold significant promise for the treatment of injured or diseased musculoskeletal tissues. However, despite advances in research, there is growing concern about the increasing number of clinical centres around the world that are making unwarranted claims or are performing risky biological procedures. Such providers have been known to recommend, prescribe, or deliver so called 'stem cell' preparations without sufficient data to support their true content and efficacy. In this annotation, we outline the current environment of stem cell-based treatments and the strategies of marketing directly to consumers. We also outline the difficulties in the regulation of these clinics and make recommendations for best practice and the identification and reporting of illegitimate providers. Cite this article: Bone Joint J 2020;102-B(2):148-154.

What this study does not prove

  • • This study does not prove SVF is an approved treatment or a replacement for standard care.
  • • This is preclinical work; animal or laboratory results cannot be applied to humans.

Evidence level

Evidence from laboratory and animal studies provides groundwork for understanding mechanisms and potential before human studies continue.

How we grade evidence
HumansMusculoskeletal DiseasesStem Cell TransplantationConsumer Product SafetyMarketing of Health ServicesAmbulatory Care FacilitiesUnited StatesPractice Guidelines as TopicPatient SafetyDirect-to-Consumer Advertising

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