Level D· Scientific groundwork from lab and animal studiesNarrative ReviewPubMed

The Role of Autologous Fat Grafting in the Treatment of Atrophic Post-Acne Scars: A Narrative Review.

Tawfik AA., Rageh MA.

Narrative Review on Scar, published in J Cutan Med Surg (2025) — summary generated from the PubMed abstract.

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Level D· Scientific groundwork from lab and animal studiesEvidence level of this study

Evidence from laboratory and animal studies provides groundwork for understanding mechanisms and potential before human studies continue.

  • Level A · Stronger Clinical Evidence
  • Level B · Emerging clinical evidence with positive signals
  • Level C · Early human research exploring benefits
  • Level D · Scientific groundwork from lab and animal studies
  • Emerging · Emerging topic under active research
Read the A–D evidence level guide

This page is generated from the PubMed record. The Thai description is an automated summary of bibliographic fields and the abstract, not a full translation, and is not medical advice.

Study type
Narrative Review
Journal
J Cutan Med Surg (2025)
Country
United States
Reported sample size
—
Source database
PubMed
PMID
39905782
DOI
10.1177/12034754251316288

Abstract (original English)

Numerous techniques have been tried to treat acne scarring. Given its filling properties and the presence of adipose tissue-derived stem cells, autologous fat has been tried for treating acne scars in multiple studies, either alone or combined with other treatment approaches. This review focuses on autologous fat grafting in its different forms, including nanofat and stromal vascular fraction, as an efficient and safe modality for treating acne scars. PubMed, Embase, and Cochrane Library databases were used to search for relevant studies published from January 2017 to December 2022. We used a combination of the following keywords: "acne scar," "acne scars," "autologous fat transplantation," "autologous fat grafting," "fat grafting for acne scars," "stromal vascular fraction," "SVF," and "nanofat." Twelve studies were found utilizing autologous fat grafting in different forms, either used alone or combined with other treatment methods such as lasers and platelet-rich plasma for treating atrophic post-acne scars. Most studies showed that autologous fat grafting effectively treated acne scars with satisfying results.

What this study does not prove

  • • This study does not prove SVF is an approved treatment or a replacement for standard care.
  • • This is a narrative review: it collects no new patient data and does not systematically appraise evidence quality.

Evidence level

Evidence from laboratory and animal studies provides groundwork for understanding mechanisms and potential before human studies continue.

How we grade evidence
HumansCicatrixAcne VulgarisAdipose TissueTransplantation, AutologousAtrophyPlatelet-Rich Plasma

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