Level D· Scientific groundwork from lab and animal studiesNarrative ReviewEurope PMCOpen access

Role of Nutritional Elements in Skin Homeostasis: A Review

Jiang N., Quan T., Li R., Chen Y., Gao T.

Narrative Review on Skin Aging, published in Biomolecules (2025) — summary generated from the PubMed abstract.

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Level D· Scientific groundwork from lab and animal studiesEvidence level of this study

Evidence from laboratory and animal studies provides groundwork for understanding mechanisms and potential before human studies continue.

  • Level A · Stronger Clinical Evidence
  • Level B · Emerging clinical evidence with positive signals
  • Level C · Early human research exploring benefits
  • Level D · Scientific groundwork from lab and animal studies
  • Emerging · Emerging topic under active research
Read the A–D evidence level guide

This page is generated from the PubMed record. The Thai description is an automated summary of bibliographic fields and the abstract, not a full translation, and is not medical advice.

Study type
Narrative Review
Journal
Biomolecules (2025)
Reported sample size
—
Source database
Europe PMC
PMID
40563448
PMCID
PMC12190690
DOI
10.3390/biom15060808
Citations
4

Abstract (original English)

Skin aging is the most prominent phenotype of human aging and is the result from the interaction of genetic and environmental factors. Improving skin aging is essential for maintaining the normal physiological function of the skin and the mental health of the human body. Existing studies have proposed many theories of aging, such as the free radical theory, mitochondrial theory of aging, etc., and accordingly have also proposed appropriate interventions. It is worth noting that many nutrients contained in the skin itself play an important role in maintaining skin health. During the aging process, a decrease in the levels of these nutrients is closely related to a weakening of the related functions. Therefore, supplementing these nutrients offers potential therapeutic options for improving skin aging. In this review, we summarize the important roles of nutrients in the skin and their potential in anti-aging, with the expectation of providing a therapeutic basis and clinical reference for delaying skin aging.

What this study does not prove

  • • This study does not prove SVF is an approved treatment or a replacement for standard care.
  • • This is a narrative review: it collects no new patient data and does not systematically appraise evidence quality.

Evidence level

Evidence from laboratory and animal studies provides groundwork for understanding mechanisms and potential before human studies continue.

How we grade evidence
SkinAnimalsHumansHomeostasisSkin AgingNutrients

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