Level D· Scientific groundwork from lab and animal studiesLaboratory StudyEurope PMC

Role of Perivascular Adipose Tissue and Exercise on Arterial Function with Obesity

Boateng SY., Olfert IM., Chantler PD.

Laboratory Study, published in Exerc Sport Sci Rev (2021) — summary generated from the PubMed abstract.

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Level D· Scientific groundwork from lab and animal studiesEvidence level of this study

Evidence from laboratory and animal studies provides groundwork for understanding mechanisms and potential before human studies continue.

  • Level A · Stronger Clinical Evidence
  • Level B · Emerging clinical evidence with positive signals
  • Level C · Early human research exploring benefits
  • Level D · Scientific groundwork from lab and animal studies
  • Emerging · Emerging topic under active research
Read the A–D evidence level guide

This page is generated from the PubMed record. The Thai description is an automated summary of bibliographic fields and the abstract, not a full translation, and is not medical advice.

Study type
Laboratory Study
Journal
Exerc Sport Sci Rev (2021)
Reported sample size
—
Source database
Europe PMC
PMID
33831902
PMCID
PMC8195847
DOI
10.1249/jes.0000000000000251
Citations
4

Abstract (original English)

Adipose tissue and arterial dysfunction are common in the obese state. Perivascular adipose tissue (PVAT) plays an important role in mediating arterial health, and with obesity, the PVAT dysfunction negatively affects arterial health. Exercise training exerts direct and beneficial effects on PVAT, providing an additional and novel pathway by which exercise can improve arterial health in diseased populations.

What this study does not prove

  • • This study does not prove SVF is an approved treatment or a replacement for standard care.
  • • This is preclinical work; animal or laboratory results cannot be applied to humans.

Evidence level

Evidence from laboratory and animal studies provides groundwork for understanding mechanisms and potential before human studies continue.

How we grade evidence
ArteriesAdipose TissueHumansObesityExerciseSignal Transduction

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