Secondary Fat Grafting in Breast Reconstruction: Comparison Between After Autologous Flap and After Silicone Implant
Mashiko T., Hattori Y., Horiguchi Y., Inoue M.
Prospective Study with a reported sample of 162, published in Plast Reconstr Surg Glob Open (2025) — summary generated from the PubMed abstract.
Early human evidence such as case series or small samples is exploring possible benefits.
- Level A · Stronger Clinical Evidence
- Level B · Emerging clinical evidence with positive signals
- Level C · Early human research exploring benefits
- Level D · Scientific groundwork from lab and animal studies
- Emerging · Emerging topic under active research
This page is generated from the PubMed record. The Thai description is an automated summary of bibliographic fields and the abstract, not a full translation, and is not medical advice.
- Study type
- Prospective Study
- Journal
- Plast Reconstr Surg Glob Open (2025)
- Reported sample size
- 162
- Source database
- Europe PMC
- PMID
- 40510434
- PMCID
- PMC12160732
- DOI
- 10.1097/gox.0000000000006866
Abstract (original English)
Background This study aimed to evaluate the impact of secondary fat grafting on patient satisfaction and well-being using the BREAST-Q, in patients who underwent flap- or implant-based breast reconstruction. Methods The patients who underwent postmastectomy breast reconstruction were divided into 4 groups based on the reconstruction technique: flap followed by fat grafting (Flap-FG), flap alone (Flap-only), implant followed by fat grafting (Imp-FG), and implant alone (Imp-only). Secondary fat grafting was performed for those dissatisfied with their initial reconstruction. One year postoperation, patients completed the BREAST-Q questionnaire, assessing breast satisfaction, outcome satisfaction, psychosocial well-being, and sexual well-being, with scores ranging from 0 to 100. Results Of the 162 patients, 139 responded to the questionnaire (response rate: 85.8%), including 14 in the Flap-FG group, 38 in the Flap-only group, 23 in the Imp-FG group, and 64 in the Imp-only group. Secondary fat grafting improved scores in both flap- and implant-reconstructed breasts, with the Imp-FG group showing significant improvements in all domains compared with the Imp-only group, including breast satisfaction ( P = 0.007), outcome satisfaction ( P = 0.041), psychosocial well-being ( P P P = 0.020) compared with the Flap-only group. The Flap-only group had higher breast satisfaction scores than
What this study does not prove
- • This study does not prove SVF is an approved treatment or a replacement for standard care.
Evidence level
Early human evidence such as case series or small samples is exploring possible benefits.
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