Level D· Scientific groundwork from lab and animal studiesNarrative ReviewEurope PMCOpen access

Silent forces, hidden currents: the influence of static magnetic field stimulation on tumor biophysics

Verma P., Varshney A., Lais M., Kalra AP.

Narrative Review, published in NPJ Biomed Innov (2026) — summary generated from the PubMed abstract.

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Level D· Scientific groundwork from lab and animal studiesEvidence level of this study

Evidence from laboratory and animal studies provides groundwork for understanding mechanisms and potential before human studies continue.

  • Level A · Stronger Clinical Evidence
  • Level B · Emerging clinical evidence with positive signals
  • Level C · Early human research exploring benefits
  • Level D · Scientific groundwork from lab and animal studies
  • Emerging · Emerging topic under active research
Read the A–D evidence level guide

This page is generated from the PubMed record. The Thai description is an automated summary of bibliographic fields and the abstract, not a full translation, and is not medical advice.

Study type
Narrative Review
Journal
NPJ Biomed Innov (2026)
Reported sample size
—
Source database
Europe PMC
PMID
42032004
PMCID
PMC13055096
DOI
10.1038/s44385-026-00071-z

Abstract (original English)

One of the prime goals of medical oncology is to find cost-effective, non-invasive cancer treatment modalities with negligible side effects. Electroceutical modalities promise to fulfill these criteria, but a precise understanding of their molecular targets is mostly unclear, limiting efficacy. Here, we review static magnetic field (SMF) stimulation for tumor treatment as a possible electroceutical modality. We start by discussing the biophysical principles through which SMFs interact with known biochemical targets and discuss evidence in support of their use for tumor treatment. We analyze the different modes of SMF stimulation and demonstrate that apparent contradictions in reported mechanisms and therapeutic outcomes are primarily due to differences in physiological conditions and biophysical stimulation parameters across studies. Finally, we provide a list of open questions that must be addressed for the success of SMF stimulation as an electroceutical modality.

What this study does not prove

  • • This study does not prove SVF is an approved treatment or a replacement for standard care.
  • • This is a narrative review: it collects no new patient data and does not systematically appraise evidence quality.

Evidence level

Evidence from laboratory and animal studies provides groundwork for understanding mechanisms and potential before human studies continue.

How we grade evidence

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