Level C· Early human research exploring benefitsCase Report / SeriesEurope PMCOpen access

Spontaneous multiple keloids: a case report

Kedar AK., Alone VD., Rathod RA., Tupkari SD., Bollineni SP., Ledwani A.

Case Report / Series on Scar, published in Pan Afr Med J (2024) — summary generated from the PubMed abstract.

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Level C· Early human research exploring benefitsEvidence level of this study

Early human evidence such as case series or small samples is exploring possible benefits.

  • Level A · Stronger Clinical Evidence
  • Level B · Emerging clinical evidence with positive signals
  • Level C · Early human research exploring benefits
  • Level D · Scientific groundwork from lab and animal studies
  • Emerging · Emerging topic under active research
Read the A–D evidence level guide

This page is generated from the PubMed record. The Thai description is an automated summary of bibliographic fields and the abstract, not a full translation, and is not medical advice.

Study type
Case Report / Series
Journal
Pan Afr Med J (2024)
Reported sample size
—
Source database
Europe PMC
PMID
39525535
PMCID
PMC11543999
DOI
10.11604/pamj.2024.48.110.43157

Abstract (original English)

An aberrant healing reaction to cutaneous injury or inflammation that spreads outside the original wound's boundaries causes keloidal scars. We present the case of a sixty-year-old male patient who initially came with complaints of respiratory system but had spontaneous lesions over his body for 50 years which remained undiagnosed. It was confirmed on histological examination to be keloids. The patient was treated with intralesional triamcinolone acetonide 40 mg plus an injection of lignocaine hydrochloride 2% in the ratio of 1:1 which provided him with a significant reduction in scar appearance over one month and thereby reducing his psychological burden. It is uncommon for spontaneous keloid scars to occur without any prior trauma or surgical intervention. Also, it details a manifestation of spontaneous keloid scars that manifest as numerous sizable lesions at various body locations. This study provides evidence in favor of such spontaneous appearance of keloid scars.

What this study does not prove

  • • This study does not prove SVF is an approved treatment or a replacement for standard care.
  • • Without an adequate control group, treatment effects cannot be separated from other factors.

Evidence level

Early human evidence such as case series or small samples is exploring possible benefits.

How we grade evidence
HumansKeloidLidocaineTriamcinolone AcetonideAnesthetics, LocalGlucocorticoidsTreatment OutcomeInjections, IntralesionalMiddle AgedMale

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